지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 67 - 72 (6page)
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초록· 키워드
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Leukotrienes (LTs) are important lipid mediators involved in allergic inflammation. The LT pathway is relatively steroid-resistant, which suggests the possibility that its blockade by alternative means may facilitate asthma management. Cysteinyl LT receptor 1 antagonists are well accepted for their efficacy and safety in asthma management. Recent studies have revealed evolving findings indicating that leukotriene B4 has an important role in the development of asthma as well as in the potential importance of cysteinyl LTs in airway remodeling. These new findings provide important clues to achieve superior control of allergic inflammation.
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등록된 정보가 없습니다.
참고문헌 (24)
참고문헌 신청
Carraro S / 2005 / Exhaled breath condensate cysteinyl leukotrienes are increased in children with exercise-induced bronchoconstriction / J Allergy Clin Immunol 115 : 764 ~
Davidson AB / 1987 / Bronchoconstrictor effects of leukotriene E4 in normal and asthmatic subjects / Am Rev Respir Dis 135 : 333 ~ 337
Drazen JM / 1999 / Treatment of asthma with drugs modifying the leukotriene pathway / N Engl J Med 340 : 197 ~ 206
Gauvreau GM / 2001 / Inhaled leukotriene E(4), but not leukotriene D(4), increased airway inflammatory cells in subjects with atopic asthma / Am J Respir Crit Care Med 164 :
Gyllfors P / 2006 / Bronchial responsiveness to leukotriene D4 is resistant to inhaled fluticasone propionate / Allergy Clin Immunol 118 : 78 ~ 83
Davidson AB / 1987 / Bronchoconstrictor effects of leukotriene E4 in normal and asthmatic subjects / Am Rev Respir Dis 135 : 333 ~ 337
Drazen JM / 1999 / Treatment of asthma with drugs modifying the leukotriene pathway / N Engl J Med 340 : 197 ~ 206
Gauvreau GM / 2001 / Inhaled leukotriene E(4), but not leukotriene D(4), increased airway inflammatory cells in subjects with atopic asthma / Am J Respir Crit Care Med 164 :
Gyllfors P / 2006 / Bronchial responsiveness to leukotriene D4 is resistant to inhaled fluticasone propionate / Allergy Clin Immunol 118 : 78 ~ 83
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