메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Background: Anisakis simplex (A. simplex) is a fish parasite which may be responsible for urticaria and anaphylaxis in case of human infections. Objective: We performed this study to identify IgE binding components and evaluate cross-allergenicity with Toxocara, a common cause of parasite allergy and Dermatophagoides pteronyssinus (D.pt). Method: Nine Anisakis allergic patients and 23 non-atopic healthy controls were enrolled. Serum specific IgE and IgG4 antibodies to A. simplex extracts were measured by ELISA. Allergenic relationships with Toxocara were evaluated by immunoCAP, IgE and IgG4 ELISA inhibition tests. IgE binding components were identified by IgE immunoblot analysis and basophil histamine release induced by A. simplexwas performed in a representative case. Result: Four of 9 A. simplex allergy patients showed high serum specific IgG4 as well as IgE antibody. No cross- reactivity between A. simplex and D.pt, or Toxocara were observed. Several IgE binding components ranged from 8 to 80 kDa were identified. A significant histamine release by A. simplex extracts was noted from basophils from the representative case. Conclusion: We confirmed that A. simplex could induce IgE mediated response which leads to urticaria and anaphylaxis in patients sensitized to A. simplex. No cross-allergenicity was observed between A. simplex and Toxocara. (Korean J Asthma Allergy Clin Immunol 2008;28:277-283)

목차

등록된 정보가 없습니다.

참고문헌 (26)

참고문헌 신청

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0