지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 254 - 258 (5page)
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초록· 키워드
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Background: The autologous serum skin test is reported to be positive in up to 60% of patients with chronic spontaneous urticaria. However, the clinical role of autologous serum skin test is still poorly understood.
Methods: We reviewed the medical records of 166 chronic spontaneous urticaria patients whose symptoms lasted for more than 6 weeks and compared their laboratory findings and medication levels according to autologous serum skin test reactivity.
Results: Autologous serum skin test was positive in 69(41.6%) chronic spontaneous urticaria patients. There were no significant differences between autologous serum skin test-positive and autologous serum skin test-negative groups in laboratory findings, such as anti-microsome antibody, anti-thyroglobulin antibody, anti-nuclear antibody, total immunoglobulin E, complement 4 level levels, rheumatoid factor,erythrocyte sedimentation rate and D-dimer. Autologous serum skin test were not related to medication levels. Eight patients (11.6%) of autologous serum skin test-positive groups and 6 patients (6.2%) of autologous serum skin test-negative groups need level 4 medication (usage of cyclosporine,dapsone or anti-immunoglobulin E monoclonal antibody) to control urticaria without statistical significance.
Conclusion: Autologous serum skin test was positive in more than 40% of chronic spontaneous urticaria patients.
However, laboratory findings and medication levels were not affected by autologous serum skin test reactivity.
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참고문헌 (24)
참고문헌 신청
Agnello V / 1983 / Partial genetic deficiency of the C4 component of complement in discoid lupus erythematosus and urticaria/ angioedema / J Am Acad Dermatol 9 : 894 ~ 898
Brunetti L / 2004 / Lospalluti ML, et al. High prevalence of autoimmune urticaria in children with chronic urticaria / J Allergy Clin Immunol 114 : 922 ~ 927
Caproni M / 2004 / Chronic idiopathic and chronic autoimmune urticaria: clinical and immunopathological features of 68 subjects / Acta Derm Venereol 84 : 288 ~ 290
Du Toit G / 2006 / Autoantibodies to the high-affinity IgE receptor in children with chronic urticaria / Ann Allergy Asthma Immunol 96 : 341 ~ 344
Ferrer M / 1999 / Complement dependence of histamine release in chronic urticaria / J Allergy Clin Immunol 104 : 169 ~ 172
Brunetti L / 2004 / Lospalluti ML, et al. High prevalence of autoimmune urticaria in children with chronic urticaria / J Allergy Clin Immunol 114 : 922 ~ 927
Caproni M / 2004 / Chronic idiopathic and chronic autoimmune urticaria: clinical and immunopathological features of 68 subjects / Acta Derm Venereol 84 : 288 ~ 290
Du Toit G / 2006 / Autoantibodies to the high-affinity IgE receptor in children with chronic urticaria / Ann Allergy Asthma Immunol 96 : 341 ~ 344
Ferrer M / 1999 / Complement dependence of histamine release in chronic urticaria / J Allergy Clin Immunol 104 : 169 ~ 172
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