지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 207 - 214 (8page)
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초록· 키워드
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Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease. It is caused by immunological abnormalities,abnormalities of the skin barrier, and environmental/genetic factors. We did a preclinical trial to identify the effects of the 633-nm light- emitting diode (LED) and 830-nm LED for AD-like lesions in NC/Nga mice.
Methods: AD-like skin lesions were induced by topical application of Dermatophagoides farinae extract on the skin of 5-week-old NC/Nga mice for 2 weeks, and then was treated with 630-nm or 830-nm LED for 1 week. We identified any therapeutic effects on AD using modified SCORAD index, skin biopsy, and measurements of both transepidermal water loss (TEWL) and proinflammatory cytokines.
Results: Both of 630-nm and 830-nm LED treatment groups showed significantly reduced SCORAD indices and TEWLs at the end of treatment, compared to the non-treatment group. In addition, the levels of proinflammatory cytokine levels in both of the LED treatment groups were significantly decreased compared to those in the non-treatment group.
Conclusion: These results show that 633-nm and 830-nm LED treatments can improve -like lesions in NC/Nga mice.
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등록된 정보가 없습니다.
참고문헌 (21)
참고문헌 신청
Ablon G / 2010 / Combination 830-nm and 633-nm light-emitting diode phototherapy shows promise in the treatment of recalcitrant psoriasis: preliminary findings / Photomed La
Barolet D / 2008 / Light-emitting diodes (LEDs) in dermatology / Semin Cutan Med Surg 27 : 227 ~ 238
Brenninkmeijer EE / 2010 / Excimer laser vs. clobetasol propionate 0·05% ointment in prurigo form of atopic dermatitis: a randomized controlled trial, a pilot / Br J Dermat
Byun HJ / 2011 / Full-spectrum light phototherapy for atopic dermatitis / Int J Dermatol 50 : 94 ~ 101
Galderhead RG / 2008 / One mechanism behind LED phototherapy for wound healing and skin rejuvenation: key role of the mast cell / Laser Therapy 17 : 141 ~ 148
Barolet D / 2008 / Light-emitting diodes (LEDs) in dermatology / Semin Cutan Med Surg 27 : 227 ~ 238
Brenninkmeijer EE / 2010 / Excimer laser vs. clobetasol propionate 0·05% ointment in prurigo form of atopic dermatitis: a randomized controlled trial, a pilot / Br J Dermat
Byun HJ / 2011 / Full-spectrum light phototherapy for atopic dermatitis / Int J Dermatol 50 : 94 ~ 101
Galderhead RG / 2008 / One mechanism behind LED phototherapy for wound healing and skin rejuvenation: key role of the mast cell / Laser Therapy 17 : 141 ~ 148
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