메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
저널정보
대한천식알레르기학회(구 대한알레르기학회) 천식 및 알레르기 천식 및 알레르기 제31권 제2호
발행연도
2011.1
수록면
84 - 90 (7page)

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Acrolein (2-propenal) is a highly reactive alpha, beta unsaturated aldehyde, and a product of lipid peroxidation reactions. It is formed from carbohydrates, amino acids,vegetable oils and animal fats during food heating or by combustion of petroleum fuels and biodiesel. It has a colorless to yellow liquid and irritating odor. Its molecular formula is C3H4O, molar mass is 56.06 g/mol, melting point is -88oC, boiling point is 53oC, and solubility is greater than 10% in water. People are exposed to acrolein via smoking,secondhand smoke, and wood/plastic smoke. Acrolein may cause irritations of eyes, nose and respiratory tract in low concentrations. The main endogenous sources of acrolein are the myeloperoxidase-mediated degradation of threonine and the amine oxidase-mediated degradation of spermine and spermidine, which may constitute a significant source of acrolein in the situations of oxidative stress and inflammation. Acrolein is metabolized by conjugation with glutathione and excreted in urine as mercapturic acid metabolites. Acrolein increases airway mucin production. Acrolein can affect tight junctional protein via FOXO1 and β-catenin. Taken together, further studies of acrolein as a constituent of cigarette smoke and an air pollutant are needed to explore their effects on asthma and lung diseases.

목차

등록된 정보가 없습니다.

참고문헌 (24)

참고문헌 신청

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0