지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 387 - 393 (7page)
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초록· 키워드
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Purpose: To evaluate the clinical results of proton beam radiation therapy (PBRT) for treatment of retinoblastoma.
Methods: Children with retinoblastoma who were treated with chemotherapy and focal treatment such as brachytherapy and thermotherapy but showed no response or developed recurrences later received PBRT. The PBRT strategy was designed to concentrate the radiation energy to the retinoblastoma and spare the surrounding healthy tissue or organs.
Results: There were three patients who received PBRT. The first patient received PBRT because of an initial lack of tumor regression with chemotherapy and brachytherapy. This patient showed regression after PBRT. The second patient who developed recurrence of retinoblastoma as diffuse infiltrating subretinal seeding was taken PBRT. After complete regression, there was recurrence of tumor and the eye was enucleated. The third patient had unilateral extensively advanced retinoblastoma. Initial chemotherapy failed and tumor recurred. The tumor responded to PBRT and regressed significantly. However, the eye developed sudden multiple recurrences, so we had to perform enucleation.
Conclusions: PBRT for retinoblastoma was effective in cases of showing no response to other treatment modalities.
However, it should be carefully applied when there was recurrence of diffuse infiltrating subretinal seeding or extensively advanced retinoblastoma initially.
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참고문헌 (25)
참고문헌 신청
Abramson DH / 2004 / Outcome following initial external beam radiotherapy in patients with Reese-Ellsworth group Vb retinoblastoma / Arch Ophthalmol 122 : 1316 ~ 1323
Bush DA / 1999 / Proton-beam radiotherapy for early-stage lung cancer / Chest 116 : 1313 ~ 1319
Croughs P / 1992 / Treatment of retinoblastoma using accelerated protons / Bull Soc Belge Ophtalmol 243 : 81 ~ 85
Crowther JG / 1974 / The cavendish laboratory 1874-1974 / Science History Publication : 181 ~
Debus J / 1997 / Brainstem tolerance to conformal radiotherapy of skull base tumors / Int J Radiat Oncol Biol Phys 39 : 967 ~ 975
Bush DA / 1999 / Proton-beam radiotherapy for early-stage lung cancer / Chest 116 : 1313 ~ 1319
Croughs P / 1992 / Treatment of retinoblastoma using accelerated protons / Bull Soc Belge Ophtalmol 243 : 81 ~ 85
Crowther JG / 1974 / The cavendish laboratory 1874-1974 / Science History Publication : 181 ~
Debus J / 1997 / Brainstem tolerance to conformal radiotherapy of skull base tumors / Int J Radiat Oncol Biol Phys 39 : 967 ~ 975
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