지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 69 - 71 (3page)
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초록· 키워드
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A 63-year-old man with a history of liver transplantation presented to our clinic complaining of visual disturbance. He had been receiving tacrolimus (FK 506) for 30 months (6 mg/day for 2 years and 3 mg/day for 6 months); he reported that the visual disturbance began while taking tacrolimus. A full ophthalmologic examination and electrophysiologic and imaging studies were performed. The best corrected visual acuity was 0.1 in both eyes. There were no abnormal finding in the anterior segment, pupillary reflexes were normal and, there was no swelling in either optic disc. Although the foveal reflex was slightly decreased, fluorescein angiography revealed non-specific signs, with the exception of a window defect. A multifocal electro-retinogram revealed decreased amplitude of the central ring.
A Swedish interactive threshold algorithm-standard 10-2 visual field test revealed a central scotoma. These findings suggest that tacrolimus may result in maculopathy. Therefore, careful ophthalmologic examination is necessary in the patients taking tacrolimus.
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등록된 정보가 없습니다.
참고문헌 (4)
참고문헌 신청
Brazis PW / 2000 / A case of bilateral optic neuropathy in a patient on tacrolimus(FK506)therapy after liver transplantation / Am J Ophthalmol 129 : 536 ~ 538
Galor A / 2007 / Maculopathy as a complication of blood-brain barrier disruption in patients with central nervous system lymphoma / Am J Ophthalmol 144 : 45 ~ 49
Kessler L / 2006 / Tacrolimus-associated optic neuropathy after pancreatic islet transplantation using a sirolimus/tacrolimus immunosuppressive regimen / Transplantation 81 :
Steg RE / 1999 / Cortical blindness and seizures in a patient receiving FK506 after bone marrow transplantation / Bone Marrow Transplant 23 : 959 ~ 962
Galor A / 2007 / Maculopathy as a complication of blood-brain barrier disruption in patients with central nervous system lymphoma / Am J Ophthalmol 144 : 45 ~ 49
Kessler L / 2006 / Tacrolimus-associated optic neuropathy after pancreatic islet transplantation using a sirolimus/tacrolimus immunosuppressive regimen / Transplantation 81 :
Steg RE / 1999 / Cortical blindness and seizures in a patient receiving FK506 after bone marrow transplantation / Bone Marrow Transplant 23 : 959 ~ 962
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