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자료유형
학술저널
저자정보
저널정보
대한안과학회 Korean Journal of Ophthalmology Korean Journal of Ophthalmology 제28권 제6호
발행연도
2014.1
수록면
473 - 478 (6page)

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Purpose: To compare the thickness of the lamina cribrosa (LC) and vascular factors of early normal-tensionglaucoma (NTG) patients with high and low intraocular pressure (IOP) that are expected to be associated withthe development of glaucoma. Methods: Seventy-one Korean NTG patients with low IOP (the highest IOP <15 mmHg, 40 patients) and highIOP (the lowest IOP >15 mmHg, 31 patients) were included in this study. The thickness of LC and vascular factorswere compared. The thickness of the LC was measured using the enhanced depth imaging method withspectral domain optical coherence tomography (Heidelberg Spectralis). Results: The mean thickness of the central LC was 190.0 ± 19.2 μm in the low IOP group and 197.8 ± 23.6 μmin the high IOP group, but there was no statistical significant difference between the two groups (p > 0.05). The prevalence of self-reported Raynaud phenomenon was significantly higher in the low IOP group (33.0%)than the high IOP group (10.3%, p = 0.04). Conclusions: The laminar thickness did not significantly differ between the high and low IOP groups. However,the prevalence of Raynaud phenomenon was higher in the low IOP groups. These results suggest that thedevelopment of glaucoma with low IOP patients may be more influenced by peripheral vasospasm, such asRaynaud phenomenon, rather than laminar thickness in NTG.

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