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자료유형
학술저널
저자정보
저널정보
대한안과학회 Korean Journal of Ophthalmology Korean Journal of Ophthalmology 제20권 제1호
발행연도
2006.1
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26 - 32 (7page)

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Purpose: To compare quantitative polarimetric measurements in eyes with NTG and HTG using GDx-VCC. Both groups were matched by age and glaucoma stage based on the Humphrey visual field test. Methods: We retrospectively reviewed the records of 146 patients who underwent Humphrey field analysis (HFA) and GDx-VCC. We compared outcomes of retinal nerve fiber layer (RNFL) parameters among the three groups by ANOVA and between each pair of groups using the Tukey-Kramer Post-Hoc test. We also evaluated the sensitivity and specificity of GDx-VCC in detecting glaucoma in each group. Results: The mean age and HFA mean deviation (MD) were 55.6±9.5 years and -0.8±1.5 dB in 47 control patients, 59.4±9.0 years and -5.77±4.38 dB in 49 NTG patients, and 59.4±11.7 years and -8.09±6.77 dB in 51 HTG patients, respectively. All thickness parameters were lower in HTG patients compared to NTG patients, but there were no significant differences in ratio parameters between age-matched early HTG and NTG patients. The sensitivity of GDx-VCC was significantly higher in both early and total HTG patients compared to the respective groups of NTG patients. Conclusions: Compared to eyes with NTG, eyes with HTG showed reduced RNFL thickness and ratio parameters when patients were age and visual field matched. GDx-VCC appeared to be more sensitive in detecting RNFL damage in HTG patients.

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