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Background/Aims: Endoscopic mucosal resection (EMR) of large colorectal lesions is associated with increased procedural time. Theobjective of this study was to evaluate the effect of double-channel gastroscope (DCG) use on the procedural time of EMRs in the rectosigmoidarea. Methods: All EMRs for sessile or flat rectosigmoid lesions ≥2 cm performed between July 2011 and September 2012 were retrospectivelyanalyzed. Results: There were 55 lesions ≥2 cm in the rectosigmoid area in 55 patients, of which 26 were removed by EMR using a DCG (DCgroup) and 29 by using an ordinary colonoscope or gastroscope (OS group). The mean size of the removed polyps, morphology, adverseeffects, and other parameters were similar between the two groups. The mean procedural time was significantly lower in the DC groupthan in the OS group (24.4±18.3 minutes vs. 36.3±24.4 minutes, p=0.015). Moreover, in a subgroup of patients with polyps >40 mm, thestatistical difference in the mean procedural time between the DC and OS groups was even more pronounced (33±21 minutes vs. 58.7±20.6 minutes, p=0.004). Conclusions: Our data suggest that the use of a DCG in the resection of large nonpedunculated rectosigmoid lesions significantly reducesthe procedural time.

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