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Background/Aims: Gastric schwannomas are rare benign mesenchymal tumors that are difficult to differentiate from othermesenchymal tumors with malignant potential, such as gastrointestinal stromal tumors. This study aimed to evaluate the characteristicfindings of gastric schwannomas via endoscopic ultrasonography (EUS). Methods: We retrospectively reviewed the EUS findings of 27 gastric schwannoma cases that underwent surgical excision at PusanNational University Hospital during 2007 to 2014. Results: Gastric schwannomas were mainly located in the middle third of the stomach with a mean tumor size of 32 mm. All lesionsexhibited hypoechoic echogenicity, and 24 lesions (88.9%) exhibited heterogeneous echogenicity. Seventeen lesions (63.0%) exhibiteddecreased echogenicity compared to the normal proper muscle layer. Distinct borders were observed in 24 lesions (88.9%), lobulatedmargins were observed in six lesions (22.2%), and marginal haloes were observed in 24 lesions (88.9%). Hyperechogenic spots wereobserved in 21 lesions (77.8%), calcifications were observed in one lesion (3.7%), and cystic changes were observed in two lesions (7.4%). Conclusions: During EUS, gastric schwannomas appear as heterogeneously hypoechoic lesions with decreased echogenicity comparedto the normal proper muscle layer. These features may be helpful for differentiating gastric schwannomas from other mesenchymaltumors.

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