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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 489 - 496 (8page)
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초록· 키워드
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ObjectiveTo describe the clinical outcomes of frozen-thawed embryo transfer (FET) with artificial preparation of theendometrium, using a combination of estrogen (E2) and progesterone (P4) with or without a gonadotropin-releasinghormone agonist (GnRHa), and the modified natural cycle (MNC) with human chorionic gonadotropin (hCG) trigger. MethodsIn this retrospective study, we evaluated 187 patients during 3 years (February 2012–April 2015). The patientswere allocated to the following treatment groups: group A, comprising 113 patients (181 cycles) who receivedGnRHa+E2+P4; group B, comprising 49 patients (88 cycles) who received E2+P4; and group C, comprising 25 patients (42cycles) who received hCG+P4. The inclusion criteria were regular menstrual cycles (length 24–35 days) and age 21–45years. ResultsThe primary outcome of the study — implantation rate (IR) per embryo transferred — was not statistically differentamong the 3 groups. Similar results were found for the IRs with fetal heartbeat per embryo transferred (68/181 [37.6%]in group A vs. 22/88 [25.0%] in group B vs. 14/42 [33.3%] in group C) and for the live birth rates (LBRs) per embryotransferred (56/181 [30.9%] in group A vs. 18/88 [20.5%] in group B vs. 11/42 [26.2%] in group C). ConclusionAlthough the pregnancy outcomes were better in the hormone therapy with GnRHa group, hormone therapy FETwith GnRHa for pituitary suppression did not result in significantly improved IRs and LBRs when compared withhormone therapy FET without GnRHa or MNC FET.
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등록된 정보가 없습니다.
참고문헌 (26)
참고문헌 신청
Trounson A / 1983 / Human pregnancy following cryopreservation, thawing and transfer of an eight-cell embryo / Nature 305:707~709
De Neubourg D / 2014 / Belgium model of coupling reimbursement of ART costs to restriction in number of embryos transferred / BMJ 348:g1559
De Neubourg D / 2013 / The history of Belgian assisted reproduction technology cycle registration and control: a case study in reducing the incidence of multiple pregnancy / Hum Reprod 28:2709~2719
Gera PS / 2010 / Ovarian hyperstimulation syndrome: steps to maximize success and minimize effect for assisted reproductive outcome / Fertil Steril 94:173~178
Check JH / 2001 / Fresh embryo transfer is more effective than frozen for donor oocyte recipients but not for donors / Hum Reprod 16:1403~1408
De Neubourg D / 2014 / Belgium model of coupling reimbursement of ART costs to restriction in number of embryos transferred / BMJ 348:g1559
De Neubourg D / 2013 / The history of Belgian assisted reproduction technology cycle registration and control: a case study in reducing the incidence of multiple pregnancy / Hum Reprod 28:2709~2719
Gera PS / 2010 / Ovarian hyperstimulation syndrome: steps to maximize success and minimize effect for assisted reproductive outcome / Fertil Steril 94:173~178
Check JH / 2001 / Fresh embryo transfer is more effective than frozen for donor oocyte recipients but not for donors / Hum Reprod 16:1403~1408
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