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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 524 - 528 (5page)
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초록· 키워드
오류제보하기
Malignant melanoma of the genital tract is a rare disease that is usually diagnosed by chance. When a definitediagnosis is delayed, the prognosis is very poor without standardized treatment. Herein, we describe a 40-yearoldpatient who presented with a history of bloody vaginal discharge for 7 months. Gynecological examinationshowed an exophytic, hard and pigmented cervical mass involving the upper vagina. The patient was diagnosedwith cervical melanoma after a punch biopsy and underwent a radical hysterectomy, upper vaginectomy, bilateralsalpingo-oophorectomy and pelvic lymphadenectomy. After surgeries, the patient underwent 2-cycles of adjuvantimmunotherapy with pembrolizumab, but died within 8 months. In this report, treatment with pembrolizumab afterradical surgery was not effective for this patient who had a primary cervical melanoma that metastasized to boneand lung tissue. We do not know why pembrolizumab was ineffective for this patient, but there are several possibleexplanations; further research is needed.
목차
등록된 정보가 없습니다.
참고문헌 (17)
참고문헌 신청
Patrick RJ / 2007 / Primary mucosal melanoma / J Am Acad Dermatol 56:828~834
Myriokefalitaki E / 2013 / Primary malignant melanoma of uterine cervix FIGO IIa1: a case report with 40 months ongoing survival and literature review / Gynecol Oncol Case Rep 5:52~54
Cid JM / 1959 / Melanoid pigmentation of the endocervix: a neurogenic visceral argument / Ann Anat Pathol (Paris) 4:617~628
Mordel N / 1989 / Malignant melanoma of the uterine cervix: case report and review of the literature / Gynecol Oncol 32:375~380
Garbe C / 2016 / Diagnosis and treatment of melanoma. European consensus-based interdisciplinary guideline - Update 2016 / Eur J Cancer 63:201~217
Myriokefalitaki E / 2013 / Primary malignant melanoma of uterine cervix FIGO IIa1: a case report with 40 months ongoing survival and literature review / Gynecol Oncol Case Rep 5:52~54
Cid JM / 1959 / Melanoid pigmentation of the endocervix: a neurogenic visceral argument / Ann Anat Pathol (Paris) 4:617~628
Mordel N / 1989 / Malignant melanoma of the uterine cervix: case report and review of the literature / Gynecol Oncol 32:375~380
Garbe C / 2016 / Diagnosis and treatment of melanoma. European consensus-based interdisciplinary guideline - Update 2016 / Eur J Cancer 63:201~217
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