지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 292 - 296 (5page)
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초록· 키워드
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Verruciform xanthoma (VX) is a rare, benign lesion that presents in the oral cavity, skin, or genital organs as a verrucous, papillomatous, or flat papule with varying colors. VX has indistinct clinical features, making histopathological examination necessary for a definitive diagnosis. Histologically, VX is characterized by parakeratosis, rete ridges with uniform depth, and an accumulation of the foam cells, which are also known as the “xanthoma cells”. These foam cells test positive for antibodies, such as CD-68 and vimentin; it is thought that VX foam cells are derived from the monocyte-macrophage lineage, and that VX’s pathogenic mechanism is partly related to an immune mechanism. Nevertheless, the pathogenesis of VX remains unclear. VX can be treated by surgical excision; other medical, chemical, and radiological treatments are not required postoperatively. Recurrence and malignant transformation of VX are rare. Two patients, each with a mass of unknown origin on the palatal gingiva, were presented at our clinic. Excisional biopsies of the masses were performed for a histological diagnosis after clinical and radiological examinations. Histological examination confirmed a diagnosis of VX in both cases.
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참고문헌 (15)
참고문헌 신청
Cumberland L / 2010 / Verruciform xanthoma in the setting of cutaneous trauma and chronic inflammation: report of a patient and a brief review of the literature / J Cutan Pa
Hu JA / 2005 / Verruciform xanthoma of the oral cavity: clinicopathological study relating to pathogenesis. Report of three cases / APMIS 113 : 629 ~ 634
Mete O / 2009 / Flat-type verruciform xanthoma of the tongue and its differential diagnosis / Dermatol Online J 15 : 5 ~
Mostafa KA / 1993 / Verruciform xanthoma of the oral mucosa: a clinicopathological study with immunohistochemical findings relating to pathogenesis / Virchows Arch A Pathol
Neville BW / 2002 / Oral & maxillofacial pathology / WB Saunders
Hu JA / 2005 / Verruciform xanthoma of the oral cavity: clinicopathological study relating to pathogenesis. Report of three cases / APMIS 113 : 629 ~ 634
Mete O / 2009 / Flat-type verruciform xanthoma of the tongue and its differential diagnosis / Dermatol Online J 15 : 5 ~
Mostafa KA / 1993 / Verruciform xanthoma of the oral mucosa: a clinicopathological study with immunohistochemical findings relating to pathogenesis / Virchows Arch A Pathol
Neville BW / 2002 / Oral & maxillofacial pathology / WB Saunders
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