지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제22권 제12호
- 발행연도
- 2012.1
- 수록면
- 1,758 - 1,766 (9page)
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초록· 키워드
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An extensive investigation was carried out to describe the kinetics of cell growth, substrate consumption, and product formation in the batch fermentation using starch as substrate. Evaluation of intrinsic kinetic parameters was carried out using a best-fit unstructured model. A nonlinear regression technique was applied for computational purpose. The Andrew’s model showed a comparatively better R2 value among all tested models. The values of specific growth rate (μmax), saturation constant (KS),inhibition constant (KI), and YX/S were found to be 0.109 h-1,11.1 g/l, 0.012 g/l, and 1.003, respectively. The Leudeking-Piret model was used to study the product formation kinetics and the process was found to be growth-associated.
The growth-associated constant (α) for protease production was sensitive to substrate concentration. Its value was fairly constant up to a substrate concentration of 30.8 g/l,and then decreased.
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참고문헌 (24)
참고문헌 신청
Andrews, J. F. / 1968 / A mathematical model for the continuous culture of microorganisms utilizing inhibitory substrates / Biotechnol. Bioeng 10 : 702 ~ 723
Anwar, A. / 2000 / Alkaline protease from Spilosoma obliqua: Potential applications in bio-formulations / Biotechnol. Appl. Biochem 31 : 85 ~ 89
Bergmeyer, H. U. / 1974 / Methods of Enzymatic Analysis, 2nd Ed / Academic Press : 1205 ~ 1212
Bhunia, B. / 2010 / Optimization of alkaline protease activity from Bacillus subtilis 2724 by response surface methodology (RSM) / Int. J. Biol. Sci. Eng 1 : 158 ~ 169
Bhunia, B. / 2010 / Selection of suitable carbon, nitrogen and sulphate source for the production of alkaline protease by Bacillus licheniformis NCIM-2042 / Not. Sci. Biol 2
Anwar, A. / 2000 / Alkaline protease from Spilosoma obliqua: Potential applications in bio-formulations / Biotechnol. Appl. Biochem 31 : 85 ~ 89
Bergmeyer, H. U. / 1974 / Methods of Enzymatic Analysis, 2nd Ed / Academic Press : 1205 ~ 1212
Bhunia, B. / 2010 / Optimization of alkaline protease activity from Bacillus subtilis 2724 by response surface methodology (RSM) / Int. J. Biol. Sci. Eng 1 : 158 ~ 169
Bhunia, B. / 2010 / Selection of suitable carbon, nitrogen and sulphate source for the production of alkaline protease by Bacillus licheniformis NCIM-2042 / Not. Sci. Biol 2
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