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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제27권 제4호
- 발행연도
- 2017.1
- 수록면
- 725 - 730 (6page)
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초록· 키워드
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A heteronemertean, Yininemertes pratensis, was collected in Han River Estuary, South Korea. This estuarine nemertean has been known by the local fishermen for harmful effects to the glass eels, juveniles of Japanese eel Anguilla japonica, migrating to fresh water. The present study confirmed the neurotoxic effects of this heteronemertean ribbon worm at the cellular level. Derivative types of neurotoxic tetrodotoxin (TTX), 5,11-dideoxy TTX (m/z 288) and 11- norTTX-6(S)-01 (m/z 305.97), were identified through HPLC and MALDI-TOF MS. However, significant neurotoxicity was confirmed in the fraction containing an undefined molecule corresponding to the 291.1 (m/z) peak, when tested in rat primary astrocytes and dorsal ganglion cells. This study is the first to report neurotoxins of the estuarine nemertean, fairly abundant in the Han River estuary, and suggests the long-term monitoring of population dynamics and surveillance of the toxicity in this river estuary.
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참고문헌 (25)
참고문헌 신청
[학술
Andrade SCS / 2011 / Disentangling ribbon worm relationships:multi-locus analysis supports traditional classification of the phylum Nemertea / Cladistics 28 : 141 ~ 159
Asakawa M / 2000 / Paralytic toxins in a ribbon worm Cephalothrix species (Nemertean) adherent to cultured oysters in Hiroshima Bay, Hiroshima Prefecture, Japan / Toxicon 38
Asakawa M / 2003 / Paralytic toxicity in the ribbon worm Cephalothrix species (Nemertea) in Hiroshima Bay, Hiroshima Prefecture, Japan and the isolation of tetrodotoxin as a
Asakawa M / 2012 / Chromatography ? The Most Versatile Method of Chemical Analysis
Andrade SCS / 2011 / Disentangling ribbon worm relationships:multi-locus analysis supports traditional classification of the phylum Nemertea / Cladistics 28 : 141 ~ 159
Asakawa M / 2000 / Paralytic toxins in a ribbon worm Cephalothrix species (Nemertean) adherent to cultured oysters in Hiroshima Bay, Hiroshima Prefecture, Japan / Toxicon 38
Asakawa M / 2003 / Paralytic toxicity in the ribbon worm Cephalothrix species (Nemertea) in Hiroshima Bay, Hiroshima Prefecture, Japan and the isolation of tetrodotoxin as a
Asakawa M / 2012 / Chromatography ? The Most Versatile Method of Chemical Analysis
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