지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제22권 제7호
- 발행연도
- 2012.1
- 수록면
- 923 - 929 (7page)
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초록· 키워드
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Optimization of culture conditions for L-asparaginase production by submerged fermentation of Aspergillus terreus MTCC 1782 was studied using a 3-level central composite design of response surface methodology and artificial neural network linked genetic algorithm. The artificial neural network linked genetic algorithm was found to be more efficient than response surface methodology.
The experimental L-asparaginase activity of 43.29 IU/ml was obtained at the optimum culture conditions of temperature 35oC, initial pH 6.3, inoculum size 1% (v/v),agitation rate 140 rpm, and incubation time 58.5 h of the artificial neural network linked genetic algorithm,which was close to the predicted activity of 44.38 IU/ml.
Characteristics of L-asparaginase production by A. terreus MTCC 1782 were studied in a 3 L bench-scale bioreactor.
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참고문헌 (21)
참고문헌 신청
Ali, S. S. / 1994 / A fungal L-asparaginase with potential antitumor activity / Ind. J. Microbiol 34 : 73 ~ 76
Baskar Gurunathan / 2011 / Design of Experiments and Artificial Neural Network Linked Genetic Algorithm for Modeling and Optimization of L-asparaginase Production by Aspergil
Baskar, G. / 2009 / Production of L-asparaginase from natural substrates by Aspergillus terreus MTCC 1782: Effect of substrate, supplementary nitrogen source and Lasparagine
Baskar, G. / 2010 / Optimization of Lasparaginase production by Aspergillus terreus MTCC 1782 using response surface methodology and artificial neural network linked genetic
Broome, J. D. / 1963 / Evidence that the L-asparaginase of guinea pig serum is responsible for its antilymphoma effects. I. Properties of the L-asparaginase of guinea pig ser
Baskar Gurunathan / 2011 / Design of Experiments and Artificial Neural Network Linked Genetic Algorithm for Modeling and Optimization of L-asparaginase Production by Aspergil
Baskar, G. / 2009 / Production of L-asparaginase from natural substrates by Aspergillus terreus MTCC 1782: Effect of substrate, supplementary nitrogen source and Lasparagine
Baskar, G. / 2010 / Optimization of Lasparaginase production by Aspergillus terreus MTCC 1782 using response surface methodology and artificial neural network linked genetic
Broome, J. D. / 1963 / Evidence that the L-asparaginase of guinea pig serum is responsible for its antilymphoma effects. I. Properties of the L-asparaginase of guinea pig ser
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