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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제19권 제10호
- 발행연도
- 2009.1
- 수록면
- 1,142 - 1,149 (8page)
이용수
초록· 키워드
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Several bioactive metabolites, including pyrrolnitrin, Nacylhomoserine
lactones, and polyhydroxyalkanoates were
isolated from Burkholderia sp. O33. Effects of various
nutrients, including sugars, gluconolactone, glycerol,
tryptophan, chloride, and zinc were investigated in relation
to the production of these metabolites. Logarithmic increase
of pyrrolnitrin was observed between 2-5 days and
reached a maximum at 7-10 days. Tryptophan concentration
reached the maximum at 3 days, whereas 7-chlorotryptophan
was gradually increased throughout the studies. Among
various carbon sources, gluconolactone, trehalose, and
glycerol enhanced pyrrolnitrin production, whereas strong
inhibitory effects were found with glucose. Relative
concentrations of pyrrolnitrin and its precursors were in
the order of pyrrolnitrin >> dechloroaminopyrrolnitrin or
aminopyrrolnitrin throughout the experiments. Among
three N-acylhomoserine lactones, the N-octanoyl analog
was the most abundant quorum sensing signal, of which
the concentrations reached the maximum in 2-3 days,
followed by a rapid dissipation to trace level. No significant
changes in pyrrolnitrin biosynthesis were observed by external
addition of N-acylhomoserine lactones. Polyhydroxyalkanoates
accumulated up to 3-4 days and decreased slowly thereafter.
According to the kinetic analyses, no strong correlations were
found between the levels of pyrrolnitrin, N-acylhomoserine
lactones, and polyhydroxyalkanoates.
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참고문헌 (24)
참고문헌 신청
Berger, E. / 1989 / PHB recovery by hypochlorite digestion / Biotechnol. Tech 3 : 227 ~ 232
Brodhagen, M. / 2004 / Positive autoregulation and signaling properties of pyoluteorin, an antibiotic produced by the biological control organism Pseudomonas fluorescens Pf-5
Byers, J. T. / 2002 / Nonenzymatic turnover of an Erwinia carotovora quorumsensing signaling molecule / J. Bacteriol 184 : 1758 ~ 1766
Chan, E. C. / 1994 / Cloning a mutated trp operon for the biosynthesis of an antibiotic agent / Biotechnol. Lett 16 : 1021 ~ 1026
Chang, C. J. / 1981 / The biosynthesis of the antibiotic pyrrolnitrin by Pseudomonas aureofaciens / J. Antibiot 34 : 555 ~ 566
Brodhagen, M. / 2004 / Positive autoregulation and signaling properties of pyoluteorin, an antibiotic produced by the biological control organism Pseudomonas fluorescens Pf-5
Byers, J. T. / 2002 / Nonenzymatic turnover of an Erwinia carotovora quorumsensing signaling molecule / J. Bacteriol 184 : 1758 ~ 1766
Chan, E. C. / 1994 / Cloning a mutated trp operon for the biosynthesis of an antibiotic agent / Biotechnol. Lett 16 : 1021 ~ 1026
Chang, C. J. / 1981 / The biosynthesis of the antibiotic pyrrolnitrin by Pseudomonas aureofaciens / J. Antibiot 34 : 555 ~ 566
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