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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제23권 제12호
- 발행연도
- 2013.1
- 수록면
- 1,802 - 1,805 (4page)
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초록· 키워드
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Ginsenosides are the most important ingredient of ginseng and are known to possess many pharmacological and biological effects. Rb1, a major protopanaxadiol ginsenoside, is the most abundant ginsenoside in Panax ginseng C.A Meyer and can be hydrolyzed into more pharmaceutically potent minor ginsenosides. To identify a microorganism that is capable of converting Rb1 into other ginsenosides, we screened 12 Microbacterium spp., and M.
trichothecenolyticum was identified as a likely candidate. M. trichothecenolyticum converted Rb1into Rd and then into Rh2 based on TLC and HPLC analyses of reaction products. This biotransformation method can be easily applied for mass production of Rd and Rh2 by using Rb1.
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참고문헌 (13)
참고문헌 신청
Cheng LQ / 2008 / Conversion of major ginsenoside Rb1 to 20(S)-ginsenoside Rg3 by Microbacterium sp. GS514 / Phytochemistry 69 : 218 ~ 224
Dong A / 2003 / Microbial transformation of ginsenoside Rb1 by Rhizopus stolonifer and Curvularia lunata / Biotechnol. Lett 25 : 339 ~ 344
Ha YW / 2006 / Qualitative and quantitative determination of ten major saponins in Platycodi radix by high performance liquid chromatography with evaporative light scattering
Hwang JT / 2007 / Anti-obesity effects of ginsenoside Rh2 are associated with the activation of AMPK signaling pathway in 3T3-L1 adipocyte / Biochem. Biophys. Res. Commun 364
Kim MW / 1987 / Distribution of saponin in various sections of Panax ginseng root and changes of its contents according to root age / Korean J. Ginseng Sci 11 : 10 ~ 16
Dong A / 2003 / Microbial transformation of ginsenoside Rb1 by Rhizopus stolonifer and Curvularia lunata / Biotechnol. Lett 25 : 339 ~ 344
Ha YW / 2006 / Qualitative and quantitative determination of ten major saponins in Platycodi radix by high performance liquid chromatography with evaporative light scattering
Hwang JT / 2007 / Anti-obesity effects of ginsenoside Rh2 are associated with the activation of AMPK signaling pathway in 3T3-L1 adipocyte / Biochem. Biophys. Res. Commun 364
Kim MW / 1987 / Distribution of saponin in various sections of Panax ginseng root and changes of its contents according to root age / Korean J. Ginseng Sci 11 : 10 ~ 16
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