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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 285 - 292 (8page)
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초록· 키워드
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In the course of study for development of functional food ingredients from aged black garlic (ABG), heat-treated ripe bulbs of Allium sativum L., the water extracts from raw-garlic (RG) and ABG, and the subsequent organic solvent fractions of ABG were prepared, and their antioxidant, antimicrobial, and antithrombosis activities were compared. The extraction yield of ABG was 4- folds higher than that of RG, and the contents of total polyphenol, total flavonoid, total sugar and reducing sugar in the ABG extract were 4-folds, 1.56-folds, 3.36-folds and 6.75-folds higher than those of the RG extract, respectively. In antioxidation activity assay, the extract of ABG showed minor scavenging activity against DPPH anion, but revealed strong scavenging activity against ABTS cation and nitrite. Especially, the ethylacetate fraction from the ABG extract demonstrated stronger antioxidation activity than the RG extract and other fractions. Although the antimicrobial and antithrombosis activities of the RG extract did not appear in the ABG extract, the ethylacetate fraction from the ABG extract had antibacterial activity against Staphylococcus aureus and Bacillus subtilis, and strong antithrombosis activity via the inhibition of prothrombin, blood coagulation factors and platelet aggregation. All extracts and fractions did not show any hemolytic activity against human red blood cells up to 5 mg/ml. Our results suggest that the ethylacetate fraction of ABG could be applicable to the development of functional food ingredients for antithrombosis agents.
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참고문헌 (32)
참고문헌 신청
Abel-Salam BK / 2012 / Immunomodulatory effects of black seeds and garlic on alloxan-induced diabetes in albino rat / Allergol. Immunopathol 40 : 336 ~ 340
Aminuddin M / 2014 / The effects of black garlic (Allium sativum L.) ethanol extract on the estimated total number of purkinje cells and motor coordination of male adolescent
Dong M / 2014 / Aged black garlic extract inhibits HT29 colon cancer cell growth via the PI3K/Akt signaling pathway / Biomed. Rep 2 : 250 ~ 254
Min Jeong Seo / 2013 / 흑마늘(Black garlic) 추출물이 마우스 비장세포의 Cytokine 생성에 미치는 영향 / 생명과학회지 23 (1) : 63 ~ 68
Purev U / 2012 / Individual differences on immunostimulatory activity of raw and black garlic extract in human primary immune cells / Immunopharmacol Immunotoxicol 34 : 651
Aminuddin M / 2014 / The effects of black garlic (Allium sativum L.) ethanol extract on the estimated total number of purkinje cells and motor coordination of male adolescent
Dong M / 2014 / Aged black garlic extract inhibits HT29 colon cancer cell growth via the PI3K/Akt signaling pathway / Biomed. Rep 2 : 250 ~ 254
Min Jeong Seo / 2013 / 흑마늘(Black garlic) 추출물이 마우스 비장세포의 Cytokine 생성에 미치는 영향 / 생명과학회지 23 (1) : 63 ~ 68
Purev U / 2012 / Individual differences on immunostimulatory activity of raw and black garlic extract in human primary immune cells / Immunopharmacol Immunotoxicol 34 : 651
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