지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제16권 제6호
- 발행연도
- 2006.1
- 수록면
- 993 - 998 (6page)
이용수
초록· 키워드
오류제보하기
We earlier suggested a hierarchical regulatory networkusing defined modeling symbols and weights in order toimprove the flux balance analysis (FBA) with regulatoryevents that were represented by if-then rules and Boleanlogic. In the present study, the simulation results of the models,which were developed and improved from the previousmodel by incorporating a hierarchical regulatory network intoan aerobic batch growth of E. coli on glucose and tryptophan.From the experimental result, a diauxic growth curve wasobserved, reflecting growth resumption, when tryptophan wasused as an alternativee after the supply of glucose was exhausted.The model parameters, the initial concentration of substrates(0.92 mM glucose and 1 mM tryptophan), cell density (0.0086 gbiomas/l), the maximal uptake rates of substrates (5.4 molglucose/g·DCW·h and 1.32 mol tryptophan/g·DCW·h), andmore accurate prediction. The simulation results agreed withthe experimental outcome of the temporal profiles of celdensity and glucose, and tryptophan concentrations.
목차
등록된 정보가 없습니다.
참고문헌 (14)
참고문헌 신청
Covert, W. C / 2001 / Regulation of gene expression in flux balance models of metabolism / J. Theor. Biol. 213 : 73 ~ 88
Covert, W. C / 2002 / Transcriptional regulation in constraints-based metabolic models of Escherichia coli / J. Biol. Chem. 277
Edwards, J. S / 2002 / Metabolic modeling of microbes: The flux-balance approach / Environ. Microbiol. 4 : 133 ~ 140
Lee, S. G / 2005 / Development of a software tool for in silico simulation of Escherichia coli using a visual programming environment / J. Biotech. 119 : 87 ~ 92
Lee, S. Y. / 1999 / Metabolic Flux Balance Analysis / Marcel Dekker, New York, U.S.A. : 13 ~ 57
Covert, W. C / 2002 / Transcriptional regulation in constraints-based metabolic models of Escherichia coli / J. Biol. Chem. 277
Edwards, J. S / 2002 / Metabolic modeling of microbes: The flux-balance approach / Environ. Microbiol. 4 : 133 ~ 140
Lee, S. G / 2005 / Development of a software tool for in silico simulation of Escherichia coli using a visual programming environment / J. Biotech. 119 : 87 ~ 92
Lee, S. Y. / 1999 / Metabolic Flux Balance Analysis / Marcel Dekker, New York, U.S.A. : 13 ~ 57
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
脫脂乳의 Tryptophan定量法에 關한 硏究
과학논집
1976 .12
-
Tryptophan 및 Tyrosine 보강 식이가 Stress로 인한 혈청 Cortisol, Glucose 및 Free Fatty Acid의 농도 변화에 미치는 영향
한국영양학회지
1990 .08
-
식이 단백질 수준 및 Tryptophan 투여가 Serotonin 대사에 미치는 영향
한국영양학회지
1993 .04
-
The urinary metabolic profiling and tryptophan pathway analysis in patients with cardiovascular disease by liquid chromatography-mass spectrometry
한국분석과학회 학술대회
2015 .11
-
초기계배 발생에 미치는 Serotonin의 영향에 관한 세포생물학적 연구
동물학회지
1987 .01
-
數種韓國常用食品中의 Tryptophan 및 Available lysine 含量에 對하여
한국영양학회지
1979 .06
-
The Gene Defective in Blue Fluorescent Arabidopsis Tryptophan Mutants.
한국동물학회 학술대회
1994 .01
-
Observation of a Diauxic Growth of Carrot Suspension Cells Grown on Mixed Carbon Sources of Malate and Glucose
한국동물학회 학술대회
1995 .01
-
Effect of Antimicrobial Peptides Containing Lysine-tryptophan Motifs on the Mammalian Membrane
한국미생물학회 학술대회논문집
2013 .05
-
Fermentative Production of Deoxyviolacein and Construction of Its Producing Strain from Improved L-Tryptophan Synthesis Pathway Escherichia coli
한국미생물학회 학술대회논문집
2015 .04
-
트립토판 합성효소의 이소조절성에 미치는 리간드
생명과학회지
2004 .02
-
Standardization of concentration of brazzein, a tryptophan-deficient sweet protein by Spectrophotometric method
한국분석과학회 학술대회
2015 .05
-
Diauxic Growth of Rice Suspesion Cells Grown on Acetate plus Glucose as Mixed Carbon Sources.
한국동물학회 학술대회
1995 .01
-
Preferential Use of Glucose during Diauxic Growth of Carrot Cells Growing on Glucose and Malate
식물학회지
1999 .01
-
Acetate-mediated change of proton gradient across plasma membrane is responsible for inhibition of glucose uptake and preferential use of acetate during acetate/glucose diauxic growth
한국동물학회 학술대회
1997 .01
-
초기 계배의 뇌형성에 미치는 몇가지 요인에 관한 세포 생물학적 연구 (1) Serotonin의 영향
동물학회지
1989 .01
-
Urinary profiling of tryptophan and it metabolites by liquid chromatography-electrospray ionization/mass spectrometry
한국분석과학회 학술대회
2015 .05
-
農, 漁, 火田部落民의 血淸蛋白組成 및 血淸 Tryptophan 含量과 營養攝取狀態와의 比較硏究
한국영양학회지
1969 .03
-
Standardization of protein concentration of brazzein, a tryptophan-deficient sweet protein by relative protein quantification using diverse methods
한국분석과학회 학술대회
2015 .11
-
비쥬얼 프로그래밍 환경을 이용한 Escherichia coli의 동적 거동 예측
한국생물정보시스템생물학회 심포지엄
2004 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0