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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제16권 제5호
- 발행연도
- 2006.1
- 수록면
- 683 - 688 (6page)
이용수
초록· 키워드
오류제보하기
We have developed a program for generatingof synthetic data sets by computer program is a usefulalternative to real data to which students and researchers havelimited aces. Uniformly-distributed-sampling clones thatwere adopted by previous programs cannot acount for thereal situation where sampled reads tend to come from particularregions of the target genome. To reflect such situation, aprobabilistic model for biased sampling distribution wasdeveloped by using an experimental data set derived from atested (varied fragment or read lengths, chimerism, andsequencing error), the extent of sequencing error was the mostcritical factor that hampered sequence assembly. We proposethat an optimum sequencing strategy employing different insertlengths and redundancy can be established by performing avariety of simulations.
목차
등록된 정보가 없습니다.
참고문헌 (15)
참고문헌 신청
Altschul, S. F / 1997 / Gapped BLAST and PSI-BLAST: A new generation of protein database search programs / Nucleic Acids Res. 25 : 3389 ~ 3402
Engle, M. L / 1994 / Artificially generated data sets for testing DNA sequence assembly algorithms / Genomics 16 : 286 ~ 288
Ewing, B / 1998 / Basecalling of automated sequencer traces using Phred. I. Accuracy assessment / Genome Res. 8 : 175 ~ 185
Huang, X / 1999 / CAP3: A DNA sequence assembly program / Genome Res. 9 : 868 ~ 877
KANG, SOON AH / 2004 / Secretory Production of Rahnella aquatilis ATCC 33071 Levansucrase Expressedin Escherichia coli / Journal of Microbiology and Biotechnology 14 (6) : 1
Engle, M. L / 1994 / Artificially generated data sets for testing DNA sequence assembly algorithms / Genomics 16 : 286 ~ 288
Ewing, B / 1998 / Basecalling of automated sequencer traces using Phred. I. Accuracy assessment / Genome Res. 8 : 175 ~ 185
Huang, X / 1999 / CAP3: A DNA sequence assembly program / Genome Res. 9 : 868 ~ 877
KANG, SOON AH / 2004 / Secretory Production of Rahnella aquatilis ATCC 33071 Levansucrase Expressedin Escherichia coli / Journal of Microbiology and Biotechnology 14 (6) : 1
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