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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제19권 제11호
- 발행연도
- 2009.1
- 수록면
- 1,342 - 1,347 (6page)
이용수
초록· 키워드
오류제보하기
We have isolated endophytic fungi from the Indian yew
tree, Taxus baccata, and then screened for taxol production.
Out of the 40 fungal cultures screened, one fungus
Gliocladium sp. was found to produce taxol and 10-DABIII
(10-deacetyl baccatin III). These compounds were purified
by TLC and HPLC and characterized using UV-spectroscopy,
ESI-MS, MS/MS, and proton NMR. One liter of Gliocladium
sp. culture yielded 10 μg of taxol and 65 μg of 10-DABIII.
The purified taxol from the fungus showed cytotoxicity
towards cancer lines HL-60 (leukemia), A431 (epidermal
carcinoma), and MCF-7 (breast cancer).
목차
등록된 정보가 없습니다.
참고문헌 (26)
참고문헌 신청
Amos, L. / 1999 / How TaxolR stabilizes microtubule structure / Chem. Biol 6 : R65 ~ R69
Biren, K. J. / 1999 / New verticillin and glisoprenin analogues from Gliocladium catenulatum, a mycoparasite of Aspergillus flavus sclerotia / J. Nat. Prod 6 : 730 ~ 733
Chan, K. C. / 1994 / High-performance liquid chromatography and micellar electrokinetic chromatography of taxol and related taxanes from bark and needle extracts of Taxus spe
Chmurny, G. N. / 1992 / 1H- and 13C-NMR assignment for taxol, 7-epi-taxol and cephalomannine / J. Nat. Prod 55 : 414 ~ 423
Edward, K. H. / 1994 / Profiling taxanes in Taxus extracts using LC/MS and LC/MS/MS techniques / J. Nat. Prod 57 : 1391 ~ 1403
Biren, K. J. / 1999 / New verticillin and glisoprenin analogues from Gliocladium catenulatum, a mycoparasite of Aspergillus flavus sclerotia / J. Nat. Prod 6 : 730 ~ 733
Chan, K. C. / 1994 / High-performance liquid chromatography and micellar electrokinetic chromatography of taxol and related taxanes from bark and needle extracts of Taxus spe
Chmurny, G. N. / 1992 / 1H- and 13C-NMR assignment for taxol, 7-epi-taxol and cephalomannine / J. Nat. Prod 55 : 414 ~ 423
Edward, K. H. / 1994 / Profiling taxanes in Taxus extracts using LC/MS and LC/MS/MS techniques / J. Nat. Prod 57 : 1391 ~ 1403
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논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
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Molecular and Morphological Characterization of a Taxol-Producing Endophytic Fungus, Gliocladium sp., from Taxus baccata
Mycobiology
2011 .01
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Taxol Production by an Endophytic Fungus, Fusarium redolens,Isolated from Himalayan Yew
Journal of Microbiology and Biotechnology
2013 .01
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Isolation, Purification, and Identification of Taxol and Related Taxanes from Taxol-Producing Fungus Aspergillus niger subsp. taxi
Journal of Microbiology and Biotechnology
2017 .01
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외래주목의 Taxol 및 관련화합물의 분석
목재공학(Journal of the Korean Wood Science and Technology)
1999 .01
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항암제 Taxol의 생산 및 이용
한국생명과학회 학술발표회
2001 .01
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The Levels of Taxol and Related Taxanes in the Korean Native Yews (Taxus cuspidata)
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1994 .01
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식물내생곰팡이의 제초활성 검정 및 소나무에서 분리한 Gliocladium catenulatum이 생산하는 제초활성 물질의 특성 규명
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Sequential administration of camptothecin sensitizes human colon cancer HCT116 cells to paclitaxel via $p21^{Cip1/WAF1}$
Animal cells and systems
2011 .01
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Screening for Antifungal Endophytic Fungi Against Six Plant Pathogenic Fungi
Mycobiology
2003 .01
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The Effect of Taxol and Ethyl-N-phenylcarbamate (EPC) on Growth and Gravitropism in Zea mays L
식물학회지
1996 .01
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한국생명과학회 심포지움
2008 .10
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Phylogenetic Analysis of the Genus Gliocladium and its Related Taxa by Comparing the Sequences of Internal Transcribed Spacers and 5.8S r-DNA
한국균학회지
1999 .01
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Endophytic Fungi as a Source of Biofuel Precursors
Journal of Microbiology and Biotechnology
2011 .01
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한국생명과학회 심포지움
2008 .10
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Diversity of Endophytic Fungi Associated with Taraxacum coreanum and Their Antifungal Activity
Mycobiology
2006 .01
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Bioprospecting of Novel and Bioactive Metabolites from Endophytic Fungi Isolated from Rubber Tree Ficus elastica Leaves
Journal of Microbiology and Biotechnology
2019 .01
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Antioxidant and Antifungal Activity of Endophytic Fungi Associated with Agarwood Trees
목재공학(Journal of the Korean Wood Science and Technology)
2019 .01
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Genetic Diversity of Endophytic Fungal Strains Isolated from the Roots of Coastal Plants in Ulleung Island for Restoration of Coastal Ecosystem
생명과학회지
2012 .10
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송이버섯과 공생하는 소나무 세근으로부터 분리된 내생균의 다양성
한국균학회지
2011 .01
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Interactions Between Biocontrol Agents and Indigenous Microorganisms in Rhizosphere of Cucumber
The Plant Pathology Journal
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