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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 1 - 6 (6page)
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CD4+ T lymphocytes play a major role in regulation of adaptive immunity. Upon activation, naïve T cells differentiate into different functional subsets. In addition to the classical Th1 and Th2 cells, several novel effector T cell subsets have been recently identified, including Th17 cells. There has been rapid progress in characterizing the development and function of Th17 cells. Here I summarize and discuss on the genetic controls of their differentiation and emerging evidence on their plasticity. This information may benefit understanding and treating immune diseases.
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참고문헌 (25)
참고문헌 신청
Akimzhanov AM / 2007 / Chromatin remodeling of interleukin-17 (IL-17)-IL-17F cytokine gene locus during inflammatory helper T cell differentiation / J Biol Chem 282 : 5969 ~
Brustle A / 2007 / The development of inflammatory TH-17 cells requires interferon- regulatory factor 4 / Nat Immunol 8 : 958 ~ 966
Chen Z / 2006 / Selective regulatory function of Socs3 in the formation of IL-17- secreting T cells / Proc Natl Acad Sci 103 : 8137 ~ 8142
Chung Y / 2009 / Critical regulation of early Th17 cell differentiation by interleukin-1 signaling / Immunity 30 : 576 ~ 587
Dong C / 2008 / TH17 cells in development: an updated view of their molecular identity and genetic programming / Nat Rev Immunol 8 : 337 ~ 348
Brustle A / 2007 / The development of inflammatory TH-17 cells requires interferon- regulatory factor 4 / Nat Immunol 8 : 958 ~ 966
Chen Z / 2006 / Selective regulatory function of Socs3 in the formation of IL-17- secreting T cells / Proc Natl Acad Sci 103 : 8137 ~ 8142
Chung Y / 2009 / Critical regulation of early Th17 cell differentiation by interleukin-1 signaling / Immunity 30 : 576 ~ 587
Dong C / 2008 / TH17 cells in development: an updated view of their molecular identity and genetic programming / Nat Rev Immunol 8 : 337 ~ 348
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