지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2010.1
- 수록면
- 805 - 810 (6page)
이용수
초록· 키워드
오류제보하기
Tumor necrosis factor receptor-related 2 (TR2, HVEM or TNFRSF-14) plays an important role in immune responses,however, the mechanisms regulating its expression are unclear. To understand the control of TR2gene expression, we studied the upstream region of the gene. Gel supershift assays revealed inducible binding of nuclear factor of activated T cells (NFAT)to a putative NFAT site within the TR2 promoter.
Furthermore, cotransfection of a dominant negative NFAT construct, or siRNA for NFAT, resulted in increased expression of a TR2 reporter gene. Our findings demonstrate that NFAT negatively regulates TR2expression in activated T cells.
목차
등록된 정보가 없습니다.
참고문헌 (18)
참고문헌 신청
Baksh S / 2002 / NFATc2- mediated repression of cyclin-dependent kanase 4 expression / Mol Cell 10 : 1071 ~ 1081
Chow CW / 1999 / Requirement for Transcription Factor NFAT in Interleukin-2 Expression / Mol Cell Biol 19 : 2300 ~ 2307
Croft M / 2003 / Co-stimulatory members of the TNFR family: keys to effective T cell immunity? / Nat Rev Immunol 3 : 609 ~ 620
Hu CM / 2002 / Modulation of T cell cytokine production by interferon regulatory factor-4 / J Biol Chem 277 : 49238 ~ 49246
Kiani A / 1997 / Down-regulation of IL-4 gene transcription and control of Th2 cell differentiation by a mechanism involving NFAT1 / Immunity 7 : 849 ~ 860
Chow CW / 1999 / Requirement for Transcription Factor NFAT in Interleukin-2 Expression / Mol Cell Biol 19 : 2300 ~ 2307
Croft M / 2003 / Co-stimulatory members of the TNFR family: keys to effective T cell immunity? / Nat Rev Immunol 3 : 609 ~ 620
Hu CM / 2002 / Modulation of T cell cytokine production by interferon regulatory factor-4 / J Biol Chem 277 : 49238 ~ 49246
Kiani A / 1997 / Down-regulation of IL-4 gene transcription and control of Th2 cell differentiation by a mechanism involving NFAT1 / Immunity 7 : 849 ~ 860
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Reactive oxygen species regulate context-dependent inhibition of NFAT5 target genes
Experimental and Molecular Medicine
2013 .01
-
Characterization of Transcriptional Activation Region of Transcription Factor NFAT
한국동물학회 학술대회
1999 .01
-
인체 지방 유래 중간엽 줄기세포의 골분화 조절 기전에서 NFAT5의 역할
생명과학회지
2013 .04
-
REGULATION AND FUNCTION OF TRANSCRIPTION FACTOR NFAT IN THE CYCLOSPORIN A-SENSITIVE EXPRESSION OF CYTOLINE GENES
한국미생물학회 학술대회논문집
1997 .04
-
Implications of Calcineurin/NFAT Inhibitors" Regulation of Dendritic Cells and Innate Immune Cells in Islet Xenotransplantation
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2016 .03
-
Nur77 inhibits TR4-induced PEPCK expression in 3T3-L1 adipocytes
Animal cells and systems
2012 .01
-
Correlation Analysis between Regulatory Sequence Motifs and Expression Profiles by Kernel CCA
한국생물정보시스템생물학회 학술대회
2005 .01
-
$V_H$ Gene Expression and its Regulation on Several Different B Cell Population by using in situ Hybridization technique
한국어병학회지
1993 .01
-
NF-kB is Involved in Platelet-Activating Factor (PAF)-Mediated Tumor Necrosis Factor (TNF)-$\alpha$ Gene Expression
한국동물학회 학술대회
1996 .01
-
고등식물의 유전자 발현의 조절
한국식물학회 심포지움
1987 .01
-
14-3-3ε protein increases matrix metalloproteinase-2 gene expression via p38 MAPK signaling in NIH3T3 fibroblast cell
Experimental and Molecular Medicine
2009 .01
-
Analysis of Hot Pepper Promoters and Gene Expression Regulation
한국유전체학회 Conference
2003 .01
-
올리고 마이크로어래이를 이용한 활성화된 인간 제대 정맥 내피세포의 유전자 발현 조사
생명과학회지
2004 .10
-
Expression of the Drosophila p38b Gene Promoter during Development and in the Immune Response
한국동물학회 학술대회
2003 .01
-
프마이크로어레이 데이터의 유전자 집합 및 대사 경로 분석
유전체소식
2006 .01
-
Transcriptome analysis and promoter sequence studies on early adipogenesis in 3T3-L1 cells
Nutrition Research and Practice
2007 .03
-
Transcriptome analysis and promoter sequence studies on early adipogenesis in 3T3-L1 cells
Nutrition Research and Practice
2007 .03
-
Informative Gene Selection Method in Tumor Classification
Genomics & informatics
2004 .01
-
Tumor Necrosis Factor Receptor Molecules in Anti-bacterial Immune Responses
한국미생물학회 학술대회논문집
2015 .04
이 논문의 저자 정보
최근 본 자료
댓글(0)
0