지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 69 - 72 (4page)
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The process of macroautophagy (referred to hereafter as autophagy), is generally characterized by the prominent formation of autophagic vesicles in the cytoplasm. In the past decades, studies of autophagy have been vastly expanded. As an essential process to maintain cellular homeostasis and functions, autophagy is responsible for the lysosome-mediated degradation of damaged proteins and organelles, and thus misregulation of autophagy can result in a variety of pathological conditions in human beings. Although our understanding of regulatory pathways that control autophagy is still limited, an increasing number of studies have shed light on the importance of autophagy in a wide range of physiological processes and human diseases. The goal of the reviews in the current issue is to provide a general overview of current knowledge on autophagy. The machinery and regulation of autophagy were outlined with special attention to its role in diabetes, neurodegenerative disorders, infectious diseases and cancer.
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참고문헌 (26)
참고문헌 신청
AAmaravadi RK / 2007 / Autophagy inhibition enhances therapy-induced apoptosis in a Mycinduced model of lymphoma / J Clin Invest 117 : 326 ~ 336
Berry DL / 2007 / Growth arrest and autophagy are required for salivary gland cell degradation in Drosophila / Cell 131 : 1137 ~ 1148
Deter RL / 1967 / Participation of lysosomes in cellular autophagy induced in rat liver by glucagon / J Cell Biol 35 : C11 ~ C16
Ebato C / 2008 / Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet / Cell Metab 8 : 325 ~ 332
Goldman SJ / 2011 / Autophagic degradation of mitochondria in white adipose tissue differentiation / Antioxid Redox Signal 14 : 1971 ~ 1978
Berry DL / 2007 / Growth arrest and autophagy are required for salivary gland cell degradation in Drosophila / Cell 131 : 1137 ~ 1148
Deter RL / 1967 / Participation of lysosomes in cellular autophagy induced in rat liver by glucagon / J Cell Biol 35 : C11 ~ C16
Ebato C / 2008 / Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet / Cell Metab 8 : 325 ~ 332
Goldman SJ / 2011 / Autophagic degradation of mitochondria in white adipose tissue differentiation / Antioxid Redox Signal 14 : 1971 ~ 1978
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