지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 90 - 98 (9page)
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초록· 키워드
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Background: Increased fasting blood glucose (FBG) level and obesity can be associated with the progression of arterial stiffness, which is an early marker of atherosclerosis. Measuring pulse wave velocity (PWV) is a non-invasive method to evaluate vessel wallstiffness.
Objective: The objective was to determine the association of FBG levels and obesity with peripheral PWV considering insulin resistance.
Methods: Across-sectional study was conducted in 2006. Waist circumference (WC), body mass index (BMI), and PWV were measured in 3,390 healthy Korean men and women. Multiple linear regression mod- els were used to assess the association between FBG levels and peripheral PWV. The population was classi- fied into two groups according to median insulin resistance values (homeostasis model assessment of insulin resistance [HOMA-IR]).
Results: Peripheral PWV was significantly associated with BMI and systolic blood pressure in men and women, respectively, after adjusting for age, lipid levels, and HOMA-IR (Table 3). WCwas associated with peripheral PWV only in women ( p =0.006). The relationship between peripheral PWV and FBG in women was significant in subjects with HOMA-IR < 0.725 ( p = 0.015).
Conclusions: These results suggest that FBG levels and waist circumference are associated with peripheral PWV in Korean women. Further studies should be performed in other populations to confirm the associa- tion between FBG levels and PWV considering insulin resistance.
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참고문헌 (20)
참고문헌 신청
Cheriyath P / 2010 / Obesity, physical activity and the development of metabolic syndrome: the atherosclerosis risk in communities study / European Journal of Cardiovascular
Cohn JN / 1999 / Vascular wall function as a risk marker for cardiovascular disease / Journal of hypertension 17 (5) : S41 ~ S44
Fang FS / 2014 / Insulin resistance correlates with the arterial stiffness before glucose intolerance / Journal of Internal Medicine 53 (3) : 189 ~ 194
Fu S / 2013 / Overall and abdominal obesity indicators had different association with central arterial stiffness and hemodynamics independent of age, sex, blood pressure, glu
Hu YH / 2011 / Increase in body mass index, waist circumference and waistto-height ratio is associated with high blood pressure in children and adolescents in China / Journal
Cohn JN / 1999 / Vascular wall function as a risk marker for cardiovascular disease / Journal of hypertension 17 (5) : S41 ~ S44
Fang FS / 2014 / Insulin resistance correlates with the arterial stiffness before glucose intolerance / Journal of Internal Medicine 53 (3) : 189 ~ 194
Fu S / 2013 / Overall and abdominal obesity indicators had different association with central arterial stiffness and hemodynamics independent of age, sex, blood pressure, glu
Hu YH / 2011 / Increase in body mass index, waist circumference and waistto-height ratio is associated with high blood pressure in children and adolescents in China / Journal
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