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논문 기본 정보

자료유형
학술저널
저자정보
저널정보
한국피부과학연구원 아시안뷰티화장품학술지 아시안뷰티화장품학술지 제11권 제6호
발행연도
2013.1
수록면
1,051 - 1,057 (7page)

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Exogeneous oxidative stress can cause rapid change of the hair follicles and melanocyte aging process, soit is an indicator of a programmed cell death (apoptosis) resulting in hair loss. In this study, effects of naturalantioxidants from wheat sprout extract on hair growth of C57BL/6 mouse (female) were evaluated. Wheatsprout and/or wheatgrass provides chlorophyll, amino acids, minerals, vitamins and enzymes. Thus it couldbe used for hair-promoting ingredients. Hydrophobic layers (80% ethanol, open column) of wheat sprout (fr. 5 and fr. 8) were used, with minoxidil (3%) on five patients as a positive control. With one week adaption, hairgrowth of 6-week old C57BL/6 mouse (female) was observed after 4 weeks of back hair removal. Transdermalextraction and hematoxylin and eosin (H&E) staining and toluidin blue staining of skin tissue were used beforeobservation with an optical microscope, which showed similar hair growth in the positive control minoxidil (3%)as wheat sprout (fr. 5), while slower in wheat sprout (fr. 8). The slaughtering cervical tissue at 4 weeks afterthe C57BL/6 mouse with wheat sprout (fr. 5) started the transition to growth. Hematoxylin & eosin stainedhistological analysis of wheat sprout (fr. 5) showed more follicles on the skin surface and smaller mast cells(shown with toluidin blue dye). In summary, wheat sprout extract (fr. 5) on C57BL/6 mouse in dermal applicationand histologic analysis promotes the hair growth, predicting an application of wheat sprout extract in a widerange of hair remedy products.

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