본 연구는 2009년 1월부터 2009년 12월까지 탈모증세가 있어 서울 강남지역에 위치한 H탈모센터를 방문하여 탈모관리를 받은 남자 47명, 여자 51명 합계 98명을 대상으로 하여 두피모낭충의 감염율과 감염도를 조사하였다. 성별 비율은 남자가 48.0%, 여자가 52.0%로 남․여 비율은 비슷했으나 여자가 남자보다 높게 나타나 탈모 발생시 여자가 남자보다 관리에 적극적인 것으로 나타났다.
조사방법은 탈모자의 외형에 따른 분류방법으로 NDM분류법에 의해 탈모자를 1기, 2기. 3기,4기로 분류하여 사용하였으며, phototrichogram법을 이용한 모주기 검사법을 사용하여 휴지기 모발비율이 15%~30%를 보통탈모, 30%~45%를 중증탈모, 45%이상을 심각 탈모의 3단계로 구분하여 분류 사용하였다. 모낭충 검사는 피지를 추출 후 0.5㎣의 피지정량기를 사용하여 모낭충 감염율과 감염도를 조사하였다. 결과는 모낭충 감염율은 63.3%로 나타났다. 외형별 분류에 의한 탈모 1기는 48%, 2기는 67%, 3기는 71%, 4기는 78%, 전체 감염율은 63.3%로 1기보다 2기, 3기, 4기의 감염율이 증가하였다. 또한 모주기에 따른 분류별 모낭충 감염율은 보통탈모 44.9%, 중증탈모 80%, 심각탈모 88.9%로, 보통탈모의 집단보다 중증 및 심각탈모의 집단에서 높게 나타났다.
모낭충 감염자 62명에 대한 모낭충 감염도는 외형별 분류에 의한 탈모 1기는 6마리/인, 2기는 6.4마리/인, 3기는 10마리/인, 4기는 12.1마리/인, 전체 감염도는 7.7마리/인으로, 1기, 2기 보다 3기, 4기의 감염도가 증가했다. 또한 모주기에 따른 분류별 모낭충 감염도는 보통탈모 4.6마리/인, 중증탈모 9.1마리/인, 심각탈모 10.4마리/인, 전체 감염도는 7.7마리/인으로 보통탈모의 집단보다 중증 및 심각탈모의 집단에서 높게 나타났다. 이러한 결과로 모낭충 감염이 탈모진행에 직접적인 원인으로 작용한다는 것을 알 수 있었으 탈모증의 예방과 치료를 위하여 모낭충의 사멸이 중요하다는 것과 두피에서의 효과적인 모낭충 제거 방법을 연구할 필요성이 요구된다는 결과를 얻었다.
This study is to investigate the affect of demodex on alopecia progress by examining the scalp demodex infection rate and its level through fixed quantity demodex examination method of alopecia subjects. Subjects of this study is total of 98 persons (47 male, 51 Female), who visited H Hair Loss (Alopecia)center that is located in Seoul Gangnam area for hair loss treatment due to alopecia symptoms between Jan.2009 to Dec.2009. Gender ratio of the subjects were similar, 48% male and 52.0% female, but showing female is slightly higher than the male, meaning that female is more actively participated in hair loss treatment when the alopecia occurs.
Investigation method of demodex infection rate and level is classification scheme based on appearance of the subjects. That is, classifying the subjects into 1st, 2nd, 3rd, and 4th by utilizing NDM classification system. Hair cycle examination through Phototrichogram was used to classify the alopecia into three stages; telogen hair ratio 15%~30% into Normal alopecia, 30%~45% into Major alopecia, and over 45% into Severe alopecia categories. For demodex examination, sebum extraction was conducted and demodex infection rate and level were examined by utilizing 0.5mm3 olfactory hair fixed quantity meter. The result showed that the demodex infection rate was 63.3%. Alopecia according to appearance classification was total 63.3%, 48% for 1st stage, 67% for 2nd, 71% for 3rd and 78% for 4th. More significant increase in infection rate was found on 2nd, 3rd, and 4t hthan the first stage. Also, demodex infection rate based on hair cycle by its classification showed that, Normal 44.9%, Major 80%, and Severe 88.9%. Significantly high infection rate was found in Major and Severe group compare to the Normal group. Demodex Infection level of 62 demodex infectee based on appearance classification scheme was total average of 7.7 per person, 6 per person for 1st stage, 6.4 per person for 2nd stage, 10 per per son for 3rd stage, and 12.1 per person for 4th stage. Infection level showed significant increase in 3rd and 4th stages compared to 1st and 2nd stages. Also, demodex infection level based on hair cycle by its classification was total average of 7.7 per person, 4.6 per person in Normal, 9.1 per person in Major, and 10.4 per person in Severe group. Significantly higher infection level was found in Major and Severe group compare to the Normal group. As a result, it is a demodex infection that acts as the direct cause of the alopecia progress. The result obtained through this study is that the elimination of demodex is very important for further prophylaxis and treatment of alopecia, and study on effective elimination of demodex in the scalp is necessary.