지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 169 - 175 (7page)
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초록· 키워드
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Turmeric (Curcuma longa L.) has been used as a spice such as curries. Although its various biological functions including anti-allergenic, and anti-carcinogenic activities were investigated, the total phenolic content of water and ethanol turmeric extracts and correlation between phenolic content and biological functions including antioxidant and anti-adipogenic activities of turmeric are relatively unknown. Here, we prepared water and ethanol turmeric extracts (W-TE and E-TE). The total phenolic content of W-TE and E-TE were 1.64%, and 9.31%, respectively. To examine the antioxidant activities of W-TE and E-TE, DPPH assay was employed. The E-TE showed strong scavenging activity against DPPH radicals than that of W-TE. The MTT assay was employed to evaluate the cytotoxicity of E-TE on 3T3-L1 cells. The treatment of 10, 25, and 50 μg/ml E-TE for 24 h dose not affect to the 3T3-L1 cell viability. Therefore, the 10 and 50 μg/ml of E-TE were chose further experiment. We also found that the 3T3-L1 adipogenesis was dose-dependently and significantly inhibited by 10, and 50 μg/ml E-TE treatment. The 50 μg/ml of E-TE suppressed 3T3-L1 adipogenesis by 71.53% when compared to adipocytes control. Moreover, the markedly suppressed lipid droplets were observed in E-TE treated 3T3-L1 adipocytes. The evidences suggest that the E-TE has the potential as a functional ingredient in the development of functional foods and nutri-cosmetics on overweight and obesity.
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참고문헌 (32)
참고문헌 신청
[학술지(정기간행물)] -
Chandler SF / 1983 / The effect of phosphate, nitrogen, and sucrose on the production of phenolics and solasidine in callus cultures of Solanum laciniatum / Plant Cell Rep 2
Chang-Ho Oh / 2010 / Effects of Heat Processing Time on Total Phenolic Content and Antioxidant Capacity of Ginseng Jung Kwa / Journal of Ginseng Research 34 (3) : 198 ~ 204
Chen HM / 1998 / Antioxidative properties of histidinecontaining peptides designed from peptide fragmentes found in the digests of a soybean protein / J. Agric. Food Chem 46
Furukawa S / 2004 / Increased oxidative stress in obesity and its impact on metabolic syndrome / J. Clin. Invest 114 : 1752 ~ 1961
Chandler SF / 1983 / The effect of phosphate, nitrogen, and sucrose on the production of phenolics and solasidine in callus cultures of Solanum laciniatum / Plant Cell Rep 2
Chang-Ho Oh / 2010 / Effects of Heat Processing Time on Total Phenolic Content and Antioxidant Capacity of Ginseng Jung Kwa / Journal of Ginseng Research 34 (3) : 198 ~ 204
Chen HM / 1998 / Antioxidative properties of histidinecontaining peptides designed from peptide fragmentes found in the digests of a soybean protein / J. Agric. Food Chem 46
Furukawa S / 2004 / Increased oxidative stress in obesity and its impact on metabolic syndrome / J. Clin. Invest 114 : 1752 ~ 1961
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