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논문 기본 정보

자료유형
학술저널
저자정보
저널정보
한국피부과학연구원 아시안뷰티화장품학술지 아시안뷰티화장품학술지 제12권 제5호
발행연도
2014.1
수록면
597 - 605 (9page)

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초록· 키워드

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The formidable barrier property of the stratum cornemum and the high hydrophilicity of active ingredientmake it difficult to permeate through the skin and reach to its site of action. So the interest of cosmeticindustry is how to promote percutaneous absorption of active ingredients. The aim of this study wasto analysis and organize theses on percutaneous absorption of active ingredient. Physical penetrationenhancers on the skin permeation is iontophoresis, electroporation, sonophoresis, tape stripping, and soon. A physical penetration enhancer that has received greater attention lately is MTS (Microneedle TherapySystem). This therapy uses micro-needle which is equipped with very thin, delicate needles smaller than a0.07 mm thick hair. During this therapy, the micro-needle makes small holes and helps absorb the solutioninto the skin. But the penetration enhancers on the skin permeation that has received the greatest attentionsince 2005 is a hoof shape method, such as pH-responsive P (MAA-co-PEGMA) hydrogel, micelle, nanoemulsion, liposome, ethosome. Especially, theses on nano emulsion and liposome (including ethosome)hold a large majority. According to the theses, the ethosome exhibited more enhanced skin permeabilitythan general liposome and ethanol solution.

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