지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 180 - 184 (5page)
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초록· 키워드
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Insulin autoimmune syndrome (IAS) is characterized by fasting hypoglycemia, endogenous hyperinsulinemia, and the presence of autoantibodies to insulin or insulin receptor in patients that have never been exposed to exogenous insulin. This syndrome is occasionally accompanied by several autoimmune disorders. There is no reported case of concurrent IAS with Hashimoto's thyroiditis. A 52-year-old female was diagnosed with Hashimoto’s thyroiditis and was treated with 25 μg/d levothyroxine for 3 years. Recently, she experienced recurrent fasting hypoglycemic symptoms that disappeared rapidly with a carbohydrate-rich diet, although she had no history of diabetes or insulin use. Blood analysis showed hypoglycemia and elevated serum levels of insulin and C-peptide. Imaging studies did not reveal a mass lesion in the pancreas, and selective calcium-stimulated venous sampling also gave a negative result. However, anti-insulin antibody titer was high and assay for anti-insulin receptor antibody was positive. Here, we report a case of IAS concomitant with Hashimoto’s thyroiditis.
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참고문헌 (20)
참고문헌 신청
19)Uchigata Y / 1993 / Patients with Graves' disease who developed insulin autoimmune syndrome (Hirata disease) possess HLA-Bw62/Cw4/DR4 carrying DRB1*0406 / J Clin Endocrin
Cho BY / 1987 / Spontaneous hypoglycemia and insulin autoantibodies in a patient with Graves' disease / Diabetes Res Clin Pract 3 (3) : 119 ~ 124
Chun SW / 2009 / A case of autoimmune hypoglycemia in the presence of both anti-insulin and anti-insulin receptor antibodies / Korean Clinical Diabetes J 10 (2) : 123 ~ 128
Cryer PE / 2009 / Evaluation and management of adult hypoglycemic disorders: an Endocrine Society Clinical Practice Guideline / J Clin Endocrinol Metab 94 (3) : 709 ~ 728
Hirata Y / 1970 / Insulin autoimmunity in a case of spontaneous hypoglycemia / J Jpn Diabetes Soc 13 : 312 ~ 320
Cho BY / 1987 / Spontaneous hypoglycemia and insulin autoantibodies in a patient with Graves' disease / Diabetes Res Clin Pract 3 (3) : 119 ~ 124
Chun SW / 2009 / A case of autoimmune hypoglycemia in the presence of both anti-insulin and anti-insulin receptor antibodies / Korean Clinical Diabetes J 10 (2) : 123 ~ 128
Cryer PE / 2009 / Evaluation and management of adult hypoglycemic disorders: an Endocrine Society Clinical Practice Guideline / J Clin Endocrinol Metab 94 (3) : 709 ~ 728
Hirata Y / 1970 / Insulin autoimmunity in a case of spontaneous hypoglycemia / J Jpn Diabetes Soc 13 : 312 ~ 320
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