중독성 갑상선 결절의 치료에 있어서 수술적 치료의 중요성

박귀숙; 오은미; 송원종; 이영돈; 정유승

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자료유형: 학술저널

저자정보: 박귀숙 오은미 송원종 이영돈 정유승

저널정보: 대한갑상선-내분비외과학회 The Journal of Endocrine Surgery The Journal of Endocrine Surgery 제13권 제3호

발행연도: 2013.1

수록면: 151 - 156 (6page)

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연구주제

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연구배경

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연구방법

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Purpose: Autonomous hyperfunctioning thyroid nodules produce thyroid hormone independently of TSH. Of these, toxic thyroid nodules provoke hyperthyroidism and can be treated by surgery or radioactive iodine therapy. The aim of this study was evaluating the role of each treatment method in Korean patients with toxic thyroid nodule.Methods: From July 2008 to June 2013, 10 patients were diagnosed with toxic thyroid nodule. We diagnosed toxic thyroid nodule by thyroid function test and thyroid scan. Thyroid function test showed hyperthyroidism. Hot nodule and suppressed uptake surrounding thyroid tissue was observed on thyroid scan. We analyzed medical records of 10 patients retrospectively.Results: 9 patients were women and 1 patient was man. Median follow-up duration was 22 months. Most common symptom was neck mass (80%) and the median tumor size was 2.66 cm. 99mTc uptake increased by 6.41% on thyroid scan. All 10 patients refused radioactive iodine therapy and 3 of these denied even operation. In 7 patients underwent thyroidectomy, 4 patients were proved having thyroid malignancy (3 papillary thyroid carcinomas and 1 follicular thyroid carcinoma). Conclusion: In Korean patients, toxic thyroid nodule was likely to accompany thyroid malignancy and radioactive iodine therapy is contraindicated in this case. Therefore, we suggested that surgery has to be considered in the first place in treatment of toxic thyroid nodule.

#자율기능성 갑상선결절 #중독성 갑상선 결절 #갑상선절제수술 #방사성요오드치료 #Autonomous hyperfunctioning thyroid nodule #Toxic thyroid nodule #Thyroidectomy #Radioactive Iodine therapy

참고문헌 (27)

참고문헌 신청

Baek JH / 2008 / Radiofrequency ablation in the treatment of an autonomously functioning thyroid nodule / J Korean Thyroid Assoc 1 : 71 ~ 73

Bahn Chair RS / 2011 / Hyperthyroidism and other causes of thyrotoxicosis: management guidelines of the American Thyroid Association and American Association of Clinical Endo

Cerci C / 2007 / Thyroid cancer in toxic and non-toxic multinodular goiter / J Postgrad Med 53 : 157 ~ 160

Cho BY / 2010 / Hyperthyroidism: other cause of thyrotoxicosis. Clinical Thyroidology / Korea Medical Book Publishing Company : 417 ~ 425

Cho NC / 1986 / Surgical treatment in thyrotoxicosis / J Korean Surg Soc 30 : 681 ~ 686