갑상선 유두암과 신체질량지수 간의 임상병리학적 관련성

나안수; 강상율; 김선광; 윤현조; 정성후

추천

검색

자료유형: 학술저널

저자정보: 나안수 강상율 김선광 윤현조 정성후

저널정보: 대한갑상선-내분비외과학회 The Journal of Endocrine Surgery The Journal of Endocrine Surgery 제14권 제4호

발행연도: 2014.1

수록면: 171 - 176 (6page)

이용수

📌

연구주제

📖

연구배경

🔬

연구방법

🏆

연구결과

이 논문의 연구 히스토리 (2)

2014

갑상선 유두암과 신체질량지수 간의 임상병리학적 관련성

나안수 , 강상율 , 김선광 외 2명 The Journal of Endocrine Surgery 2014.01 학술저널

2013

신체질량지수와 유두상 갑상선암의 임상병리학적 연관성

나안수 의학 2013.01 학위논문

이 논문의 후속연구가 궁금하신가요?
연관 학술논문 또는 학술발표를 통해 보다 발전된 연구결과를 확인하실 수 있습니다.
이 논문의 연구 히스토리 확인하기

초록· 키워드

오류제보하기

Purpose: Obesity is a known risk factor for several cancers, including breast, colon, esophagus, kidney, uterus, and thyroid. Recent studies have reported that higher body mass index (BMI) is also associated with more advanced stage. The aim of this study was to investigate the clinicopathological relevance between BMI and papillary thyroid carcinoma (PTC). Methods: A total of 798 patients surgically treated for PTC from January 2006 to June 2010 were included in this study. Medical records and pathologic reports were reviewed retrospectively. According to BMI, patients were divided into four groups: underweight (3.1%), normal (57.3%), overweight (31.6%), and obese (8.0%). Clinicopathological factors were analyzed and compared between normal and other groups. Results: According to the results, 709 patients were women (89.0%) and mean age was 48.5 years; mean follow-up period was 1,721±464.2 days. In comparison between the normal and underweight groups, there was significantly more extra-thyroidal invasion [Odds ratio (OR) 3.923, P=0.006] in the underweight group. In the obese group, tumor size was significantly larger (OR 1.794, P=0.007). However, there was no significant difference between the normal and overweight group. Conclusion: In the obese group, tumor size was the only clinical significant factor between high BMI and PTC. Interestingly, more extra-thyroidal invasion was seen in the underweight group. To confirm this result, further studies with long-term follow-up and more patients are required.

#비만 #신체질량지수 #갑상선 유두암 #Obesity #Body mass index #Papillary thyroid carcinoma

참고문헌 (25)

참고문헌 신청

Alvarez-Castro P / 2011 / Endocrine function in obesity / Endocrinol Nutr 58 : 422 ~ 432

Brindel P / 2009 / Anthropometric factors in differentiated thyroid cancer in French Polynesia: a case-control study / Cancer Causes Control 20 : 581 ~ 590

Chen AY / 2009 / Increasing incidence of differentiated thyroid cancer in the United States, 1988-2005 / Cancer 115 : 3801 ~ 3807

De Pergola G / 2013 / Obesity as a major risk factor for cancer / J Obes 2013 : 291546 ~

Edge SB / 2010 / AJCC cancer staging manual / Springer