유두상 갑상선 암 환자에서 수술 전 혈청 호중구-림프구 비의 임상적 의의

오행진; 장여구; 홍성우; 이우용; 이병모

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자료유형: 학술저널

저자정보: 오행진 장여구 홍성우 이우용 이병모

저널정보: 대한갑상선-내분비외과학회 The Journal of Endocrine Surgery The Journal of Endocrine Surgery 제14권 제4호

발행연도: 2014.1

수록면: 190 - 194 (5page)

이용수

📌

연구주제

📖

연구배경

🔬

연구방법

🏆

연구결과

이 논문의 연구 히스토리 (2)

2015

갑상선 유두암 환자에서 수술 전 혈청 염증 관련 인자들의 임상적 유의성

오행진 의학과 외과학 전공 2015.01 학위논문

2014

유두상 갑상선 암 환자에서 수술 전 혈청 호중구-림프구 비의 임상적 의의

오행진 , 장여구 , 홍성우 외 2명 The Journal of Endocrine Surgery 2014.01 학술저널

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Purpose: Papillary thyroid cancer (PTC) is known to have a favorable prognosis and low mortality. However, some PTC has aggressive propensity with loco-regional recurrence or distant metastasis, and it could cause poor quality of life. Many studies for predicting high-risk group in papillary thyroid cancer have been reported, however, more study is needed. The objective of this study is to assess the efficiency of inflammation indices including the Neutrophil-Lymphocyte Ratio (NLR) as a predictor for high-risk group in papillary thyroid cancer patients. Methods: From January 2006 to November 2012, this study enrolled consecutive 164 patients who underwent total thyroidectomy and were confirmed with papillary thyroid cancer by histopathology. Among 164 patients, 23 were excluded because they had co-morbidities which could confound the inflammation related variables. We reviewed the medical records of 141 patients and assessed the correlation between inflammation indices including preoperative serum NLR and clinical prognostic parameters, including age at presentation, tumor size, extra-thyroidal extension, lymph node metastasis, TNM stage, and MACIS score. Results: In the papillary thyroid cancer patients, preoperative value of NLR, ESR, CRP, platelet, and albumin showed no significant correlation with the risk factors. Conclusion: In this study, preoperative inflammatory parameters such as NLR had uncertain efficacy as risk factors for papillary thyroid cancer.

#염증 #예후 #유두상 갑상선 암 #Inflammation #Prognosis #Papillary thyroid cancer

참고문헌 (25)

참고문헌 신청

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Barbaro D / 2014 / The BRAF V600E mutation in papillary thyroid cancer with positive or suspected pre-surgical cytological finding is not associated with advanced stages or w

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