갑상선 결절의 진단에서 양전자방출 단층촬영의 유용성

서수연; 김지훈; 김준영; 고영택; 변창규; 이병찬; 구민영

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자료유형: 학술저널

저자정보: 서수연 김지훈 김준영 고영택 변창규 이병찬 구민영

저널정보: 대한갑상선-내분비외과학회 The Journal of Endocrine Surgery The Journal of Endocrine Surgery 제12권 제4호

발행연도: 2012.1

수록면: 239 - 243 (5page)

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Purpose: Whole body Positron Emission Tomography (PET) was used to evaluate the existence of cancer cells. However, PET had limitations in identifying thyroid cancer cells because of their slow progression, and evidence regarding its accuracy in finding thyroid cancer cells is insufficient. Therefore, we investigated the usefulness of PET for evaluation of patients with thyroid nodules by studying the relationships between PET and thyroid ultrasonography. Methods: We evaluated 4,627 patients who had undergone PET from January 2007 to October 2011 and selected 370 patients who had undergone thyroid ultrasonography. We compared and analyzed the amount of thyroid SUVmax of PET, the pattern of glucose uptake, and findings of thyroid ultrasonography based on their size, shape, location, and FNAC. Results: Of 370 patients, 197 (53.2%) subjects were found to have thyroid nodules, and 211 (57.0%) subjects had higher sugar metabolism, regardless of having thyroid nodules. No statistical correlations were observed among nodule size, nodule location,and higher sugar metabolism, however, noticeable relationships were observed between the shape of the cells on thyroid ultrasonography and FDG uptake of PET. In cases of papillary thyroid cancer, there was higher FDG uptake, compared to benign lesions in particular, SUVmax of the papillary thyroid cancer showed a significantly elevated level of FDG uptake. Conclusion: Despite its limited usefulness in identifying the characteristics of thyroid nodules being benign or malignant, PET is appropriate for evaluation of the malignancy of thyroid cells.

#갑상선암 #양전자방출 단층촬영 #갑상선 우연종 #Thyroid cancer #Positron emission tomography #Incidentaloma

참고문헌 (19)

참고문헌 신청

Bae JS / 2009 / Incidental thyroid lesions detected by 18F-FDG PET/CT: prevalence and risk of thyroid cancer / World J Surg Oncol 7 : 63 ~

Baek JB / 2009 / The correlation between the fine needle aspiration cytology and histology of patients who have undergone thyroidectomy / Korean J Endocrine Surg 9 : 223 ~ 2

Chen YK / 2005 / Prevalence and risk of cancer of focal thyroid incidentaloma identified by 18F-fluorodeoxyglucose positron emission tomography for cancer screening in healt

Chen YK / 2005 / Prevalence and risk of cancer of focal thyroid incidentaloma identified by 18F-fluorodeoxyglucose positron emission tomography for cancer screening in health

Chu QD / 2006 / Positron emission tomography (PET) positive thyroid incidentaloma: the risk of malignancy observed in a tertiary referral center / Am Surg 72 : 272 ~ 275