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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 98 - 101 (4page)
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초록· 키워드
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Purpose: Today, many urologists use nucleic acid amplification tests (NAAT) in diagnosis of Chlamydia trachomatis infection in Korea. A new variant of C. trachomatis with a deletion in the cryptic plasmid, which cannot be detected using commercial tests targeting the deleted DNA sequences, has been found in Sweden. Therefore, the partial deletion of cryptic plasmid DNA means that the diagnostic standards cannot detect chlamydial infection any more in cases of new mutants. The mutant type has been prevalent in Sweden, however, its incidence was not high in other countries such as France, Holland, and Denmark. In or to study the existence of this mutant C. trachomatis in Korea, we developed new primer sets for detection of this mutation. Materials and Methods: We collected the first voided urine from male urethritis patient from April 2012 to August 2013 (Dankook University Hospital, Cheonan, Korea). We used the 25 confirmed C. trachomatis-positive specimens by using KL1 and KL2 primers for C. trachomatis and tested the existence of mutant chlamydial infection with the newly developed primer sets. Results: We could not detect any new variant in the samples. Conclusions: Although this mutant C. trachomatis is not seen in Korea, we should watch for the occurrence of the type in the future. I would like to briefly report on implications of the surging mutant forms and how we might attain an understanding of this phenomenon.
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참고문헌 (15)
참고문헌 신청
/ 1999 / National guideline for the management of Chlamydia trachomatis genital tract infection. Clinical Effectiveness Group (Association of Genitourinary Medicine and the
Byun Y / 2008 / Differences in Chlamydia trachomatis cryptic plasmid loads in two types of female commercial sex workers in Korea / Jpn J Infect Dis 61 : 146 ~ 147
Davis JD / 1998 / A comparison of ligase chain reaction to polymerase chain reaction in the detection of Chlamydia trachomatis endocervical infections / Infect Dis Obstet Gy
Groseclose SL / 1999 / Estimated incidence and prevalence of genital Chlamydia trachomatis infections in the United States, 1996 / Sex Transm Dis 26 : 339 ~ 344
Hoffmann S / 2007 / Mutant Chlamydia trachomatis in Denmark / Euro Surveill 12 : E7 ~ 8
Byun Y / 2008 / Differences in Chlamydia trachomatis cryptic plasmid loads in two types of female commercial sex workers in Korea / Jpn J Infect Dis 61 : 146 ~ 147
Davis JD / 1998 / A comparison of ligase chain reaction to polymerase chain reaction in the detection of Chlamydia trachomatis endocervical infections / Infect Dis Obstet Gy
Groseclose SL / 1999 / Estimated incidence and prevalence of genital Chlamydia trachomatis infections in the United States, 1996 / Sex Transm Dis 26 : 339 ~ 344
Hoffmann S / 2007 / Mutant Chlamydia trachomatis in Denmark / Euro Surveill 12 : E7 ~ 8
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