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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 86 - 92 (7page)
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Recurrent urinary tract infection is a common infectious disease seen in the clinic. It is very prevalent in women; as many as 15% of women develop urinary tract infection each year, and at least 25% have one or more recurrences. Chronic inflammation and increased urothelial apoptosis reflect a common patho-physiology in various lower urinary tract dysfunctions, causing bladder storage symptoms. It has been suggested that chronic inflammation could be associated with overactive detrusor and increased levels of urinary nerve growth factor and creatinine. The level of urinary nerve growth factor may decrease after an effective antimuscarinic therapy. Recurrent urinary tract infection could be prevented by using nonsteroidal anti-inflammatory drugs or cyclooxygenase-2 inhibitors. Intravesical hyaluronate and chondroitin sulfate reduce the incidence of recurrent bacterial cystitis, and treatment with hyaluronate targets bacterial adherence to the bladder mucosa in interstitial cystitis/bladder pain syndrome. This article reviews the pathophysiology of chronic inflammation of the bladder and investigates the association between chronic inflammation and recurrent urinary tract infection.
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참고문헌 (58)
참고문헌 신청
최현섭 / 2016 / National Trends of Antimicrobial Resistance in Uncomplicated Cystitis / Urogenital Tract Infection 11(1):7~11
Grover S / 2011 / Role of inflammation in bladder function and interstitial cystitis / Ther Adv Urol 3:19~33
Liu HT / 2015 / Alteration of urothelial Inflammation, apoptosis, and junction protein in patients with various bladder conditions and storage bladder symptoms suggest common pathway involved in underlying pathophysiology / Low Urin Tract Symptoms 7:102~107
Liu HT / 2013 / Increased serum adipokines implicate chronic inflammation in the pathogenesis of overactive bladder syndrome refractory to antimuscarinic therapy / PLoS One 8:e76706
Tyagi P / 2010 / Urine cytokines suggest an inflammatory response in the overactive bladder : a pilot study / Int Urol Nephrol 42:629~635
Grover S / 2011 / Role of inflammation in bladder function and interstitial cystitis / Ther Adv Urol 3:19~33
Liu HT / 2015 / Alteration of urothelial Inflammation, apoptosis, and junction protein in patients with various bladder conditions and storage bladder symptoms suggest common pathway involved in underlying pathophysiology / Low Urin Tract Symptoms 7:102~107
Liu HT / 2013 / Increased serum adipokines implicate chronic inflammation in the pathogenesis of overactive bladder syndrome refractory to antimuscarinic therapy / PLoS One 8:e76706
Tyagi P / 2010 / Urine cytokines suggest an inflammatory response in the overactive bladder : a pilot study / Int Urol Nephrol 42:629~635
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