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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 36 - 40 (5page)
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Purpose: The purpose of this study is to evaluate efficacy of Collatamp (EUSA Pharma [Europe]; a gentamicin-containing collagen implant, GCCI) in pediatric urologic surgery. Materials and Methods: The study comprised a retrospective analysis of 35 consecutive children who underwent pediatric urologic surgery for treatment of hydrocele, undescended testis and varicocele between March 2013 and March 2015. Collatamp containing 130 mg gentamicin and 280 mg collagen were immersed in 300 ml normal saline for up to 6 hours. At set times after immersion the GCCI were removed, the saline diluted in normal human serum and the gentamicin content assayed by a validated immunoassay (Cedia, Microgenics Ltd., UK) to provide an estimate of the loss from each implant. Patients were classified according to two groups: patients with Collatamp (group A) and those without Collatamp (group B). Postoperative complication, operative time and age, etc. were assessed at postoperative 7 days.Results: Sixteen hydrocele, 16 undescended testis, and 3 varicocele patients were identified, with a median age of 87.43±54.10 months, operation time of 103.60±29.41 minutes, and hospitalization period of 3.20±0.68 days. Mean age, operation time, and hospitalization period in group A, B was 64.81±60.32 months, 100.80±46.80 months (p=0.02), 122.30±40.70 minutes, 103.61±29.39 minutes (p=0.17), and 3.20±0.40 days, 3.20±0.80 days (p=0.67), respectively. No statistically significant differences in postoperative complication were observed between the two groups. However, cost was higher in group A than in group B (300,000 won vs, 15,900.82±3,905.72 won).Conclusions: Collatamp may be useful and effective in preventing wound infection in pediatric urologic surgery, although Collatamp is more expensive.
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참고문헌 (17)
참고문헌 신청
Bennett-Guerrero E / 2010 / Gentamicin-collagen sponge for infection prophylaxis in colorectal surgery / N Engl J Med 363 : 1038 ~ 1049
Bratzler DW / 2005 / Antimicrobial prophylaxis for surgery: an advisory statement from the National Surgical Infection Prevention Project / Am J Surg 189 : 395 ~ 404
Chang WK / 2013 / Gentamicin-collagen implants to reduce surgical site infection: systematic review and meta-analysis of randomized trials / Ann Surg 258 : 59 ~ 65
Chung JM / 2010 / The use of prophylactic antibiotics in pediatric urologic surgery: a questionnaire survey of pediatric urologist in Korea / J Korean Pediatr Urol 2 : 29 ~
Espin-Basany E / 2005 / Prospective, randomised study on antibiotic prophylaxis in colorectal surgery. Is it really necessary to use oral antibiotics / Int J Colorectal Dis 2
Bratzler DW / 2005 / Antimicrobial prophylaxis for surgery: an advisory statement from the National Surgical Infection Prevention Project / Am J Surg 189 : 395 ~ 404
Chang WK / 2013 / Gentamicin-collagen implants to reduce surgical site infection: systematic review and meta-analysis of randomized trials / Ann Surg 258 : 59 ~ 65
Chung JM / 2010 / The use of prophylactic antibiotics in pediatric urologic surgery: a questionnaire survey of pediatric urologist in Korea / J Korean Pediatr Urol 2 : 29 ~
Espin-Basany E / 2005 / Prospective, randomised study on antibiotic prophylaxis in colorectal surgery. Is it really necessary to use oral antibiotics / Int J Colorectal Dis 2
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