지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 422 - 427 (6page)
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초록· 키워드
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Purpose: To compare the effect of humidified high flow nasal cannula (HHFNC) with that of nasal continuous positive airway pressure (NCPAP) as the mode of extubation in very low birth weight infants (VLBWI).
Methods: Medical records were retrospectively reviewed for 219 VLBWI who were admitted to the neonatal intensive care unit of Ajou University Hospital from January 2009 through December 2012; 87 were supported by noninvasive ventilation (NIV) after extubation (HHFNC n=47, NCPAP n=40). Extubation failure was defined as the need for reintubation within 1 week of extubation.
Results: (1) There were no significant differences between the groups in demographic data such as gestational age, birth weight, and age at extubation. (2) There were no significant differences in fraction of inspired oxygen (FiO2) (HHFNC 0.23±0.03 vs. NCPAP 0.23±0.03, P-value .937) and peak inspiratory pressure (HHFNC 11±6.6 cmH2O vs. NCPAP 10.3±3.4 cmH2O, P-value .559) before extubation. (3) The rate of extubation failure and FiO2 values after extubation were similar in the 2 groups (extubation failure, HHFNC 5/47 vs. NCPAP 5/40, P-value 1.000; FiO2, HHFNC 0.24±0.05 vs. NCPAP 0.25±0.04, P-value .399). (4) Among patients who received NIV after extubation once but did not receive further intubation, the duration of NIV or duration of oxygen supply were not significantly different between the groups (NIV, HHFNC 12.4±9.1 days vs. NCPAP 8.7±12.3 days, P-value .159, oxygen supply, HHFNC 49.0±40.3 days vs. NCPAP 50.9±41.3 days, P-value .844) or bronchopulmonary dysplasia rate (HHFNC 24.3% vs. NCPAP 34.4%, P-value .430).
Conclusion: HHFNC is as effective as NCPAP for weaning VLBWIs from invasive mechanical ventilation.
목차
등록된 정보가 없습니다.
참고문헌 (18)
참고문헌 신청
Andrade FH / 2008 / Noninvasive ventilation in neonates: the lungs don’t like it! / J Appl Physiol(1985) 105 : 1385 ~ 1386
Campbell DM / 2006 / Nasal continuous positive airway pressure from high flow cannula versus Infant Flow for Preterm infants / J Perinatol 26 : 546 ~ 549
De Paoli AG / 2003 / Nasal CPAP for neonates: what do we know in 2003? / Arch Dis Child Fetal Neonatal Ed 88 : F168 ~ F172
Frey B / 2001 / Nasopharyngeal oxygen therapy produces positive end-expiratory pressure in infants / Eur J Pediatr 160 : 556 ~ 560
Holleman-Duray D / 2007 / Heated humidified high-flow nasal cannula: use and a neonatal early extubation protocol / J Perinatol 27 : 776 ~ 781
Campbell DM / 2006 / Nasal continuous positive airway pressure from high flow cannula versus Infant Flow for Preterm infants / J Perinatol 26 : 546 ~ 549
De Paoli AG / 2003 / Nasal CPAP for neonates: what do we know in 2003? / Arch Dis Child Fetal Neonatal Ed 88 : F168 ~ F172
Frey B / 2001 / Nasopharyngeal oxygen therapy produces positive end-expiratory pressure in infants / Eur J Pediatr 160 : 556 ~ 560
Holleman-Duray D / 2007 / Heated humidified high-flow nasal cannula: use and a neonatal early extubation protocol / J Perinatol 27 : 776 ~ 781
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