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지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 191 - 195 (5page)
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초록· 키워드
오류제보하기
Leukocyte adhesion deficiency is a rare primary immunodeficiency and autosomal recessive disorder caused by a mutation in the gene encoding CD18, which is a constituent of leukocyte integrins. Clinical features usually begin with a delay in the separation of the umbilical cord in the neonatal period, and are characterized by marked leukocytosis with infection, delayed wound healing, and repeated bacterial and fungal infections. We experienced a case of leukocyte adhesion deficiency diagnosed in the neonatal period, in which a late preterm infant admitted to neonatal intensive care unit presented with a septic hip. Flow cytometry analysis of whole blood showed a decrease in the expression of CD11b/CD18. This is the first case of leukocyte adhesion deficiency with neonatal septic hip diagnosed in Korea.
목차
등록된 정보가 없습니다.
참고문헌 (16)
참고문헌 신청
van de Vijver E / 2012 / Hematologically important mutations: leukocyte adhesion deficiency (first update) / Blood Cells Mol Dis 48:53~61
Hanna S / 2012 / Leukocyte adhesion deficiencies / Ann N Y Acad Sci 1250:50~55
Lorusso F / 2006 / Preimplantation genetic diagnosis of leukocyte adhesion deficiency type I / Fertil Steril 85:494
Hayward AR / 1979 / Delayed separation of the umbilical cord, widespread infections, and defective neutrophil mobility / Lancet 1:1099~1101
Kabak S / 2002 / Septic arthritis in patients followed-up in neonatal intensive care unit / Pediatr Int 44:652~657
Hanna S / 2012 / Leukocyte adhesion deficiencies / Ann N Y Acad Sci 1250:50~55
Lorusso F / 2006 / Preimplantation genetic diagnosis of leukocyte adhesion deficiency type I / Fertil Steril 85:494
Hayward AR / 1979 / Delayed separation of the umbilical cord, widespread infections, and defective neutrophil mobility / Lancet 1:1099~1101
Kabak S / 2002 / Septic arthritis in patients followed-up in neonatal intensive care unit / Pediatr Int 44:652~657
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