지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 59 - 63 (5page)
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초록· 키워드
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Congenital chloride diarrhea (CCD) is a rare autosomal recessive disease, which is characterized by electrolyte absorption defect due to impaired function of the Cl-/HCO3- exchanger in the ileum and the colon. Its main features are profuse watery diarrhea, high fecal chloride concentration, and failure to thrive. Profuse watery diarrhea characterized by a high concentration of chloride in stools results in hypo- chloremia, hyponatremia, and dehydration with metabolic alkalosis. Early detection and therapeutic intervention can prevent life-threatening symptoms of CCD and growth failure. Recently, several therapies, such as proton pump inhibitors and buty- rate, have been suggested for amelioration of diarrhea. Here, we report a case of CCD in a preterm male infant who was successfully treated with an oral proton pump inhibitor.
목차
등록된 정보가 없습니다.
참고문헌 (19)
참고문헌 신청
Darrow DC / 1945 / Congenital alkalosis with diarrhea / J Pediatr 26:519~532
Gamble JL / 1945 / Congenital alkalosis with diarrhea / J Pediatr 26:509~518
Wedenoja S / 2010 / Review article: the clinical management of congenital chloride diarrhoea / Aliment Pharmacol Ther 31:477~485
Hoglund P / 1998 / Genetic background of congenital chloride diarrhea in high-incidence populations: Finland, Poland, and Saudi Arabia and Kuwait / Am J Hum Genet 63:760~768
Hong J / 2013 / Congenital chloride diarrhea in Korean children: novel mutations and genetic characteristics / Eur J Pediatr 172:545~550
Gamble JL / 1945 / Congenital alkalosis with diarrhea / J Pediatr 26:509~518
Wedenoja S / 2010 / Review article: the clinical management of congenital chloride diarrhoea / Aliment Pharmacol Ther 31:477~485
Hoglund P / 1998 / Genetic background of congenital chloride diarrhea in high-incidence populations: Finland, Poland, and Saudi Arabia and Kuwait / Am J Hum Genet 63:760~768
Hong J / 2013 / Congenital chloride diarrhea in Korean children: novel mutations and genetic characteristics / Eur J Pediatr 172:545~550
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