지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 238 - 243 (6page)
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초록· 키워드
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Objectives: There is a lack of data on bone loss in premenopausal patients with breast cancer after chemotherapy in Korea. In this study, we compared the bone mineral density of breast cancer patients after chemotherapy with normal control.
Materials and Methods: We used the data from the fourth Korea National Health and Nutrition Examination Survey (KNHNES) as normal control, and 119 women were enrolled who had surgery and chemotherapy due to breast cancer. They were under the age of 50 and premenopausal state according to their FSH level. Bone mineral density (BMD) was measured by dual-energy X-ray absorptiometry.
Results: T-score at Lumbar spine BMD was not different between breast cancer group and control group (0.16±0.98 vs 0.08±1.00, P=0.451). And neither did T-score at femoral neck (-0.18±1.09 vs -0.27±0.95, P=0.419). T-score at total hip BMD was significantly different between two groups (0.26±0.97 vs 0.64±0.91, P<0.001). After adjustment of age and body mass index, the significance still remained (P<0.001 and P=0.001, respectively). The prevalence of bone loss (osteopenia and osteoporosis) at total hip was higher in breast cancer group than control group (10.1% vs 5.5%, P=0.012)Conclusions: The patients with breast cancer needs to evaluate the bone mineral density at total hip even if they are premenopausal states.
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참고문헌 (15)
참고문헌 신청
/ 2006 / Nationwide Korean Breast Cancer Data of 2004 Using Breast Cancer Registration Program 9 : 151 ~ 161
Ahn SH / 1999 / Relation between body size and body mass index and breast cancer by menopausal status in Korea 31 : 72 ~ 81
Bruning PF / 1990 / Bone mineral density after adjuvant chemotherapy for premenopausal breast cancer / Br J Cancer 61 : 308 ~ 310
Goldhirsch A / 2007 / Progress and promise: highlights of the international expert consensus on the primary therapy of early breast cancer 2007 / Ann Oncol 18 : 1133 ~ 1144
Hadji P / 2009 / The influence of chemotherapy on bone mineral density, quantitative ultrasonometry and bone turnover in pre-menopausal women with breast cancer / Eur J Cance
Ahn SH / 1999 / Relation between body size and body mass index and breast cancer by menopausal status in Korea 31 : 72 ~ 81
Bruning PF / 1990 / Bone mineral density after adjuvant chemotherapy for premenopausal breast cancer / Br J Cancer 61 : 308 ~ 310
Goldhirsch A / 2007 / Progress and promise: highlights of the international expert consensus on the primary therapy of early breast cancer 2007 / Ann Oncol 18 : 1133 ~ 1144
Hadji P / 2009 / The influence of chemotherapy on bone mineral density, quantitative ultrasonometry and bone turnover in pre-menopausal women with breast cancer / Eur J Cance
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