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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 61 - 66 (6page)
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Objective: We investigated the clinical and electrophysiological expressions of the thenar muscular atrophy in patients with amyotrophic lateral sclerosis (ALS) and evaluated whether the selective involvement of thenar muscles was caused by the split hand phenomenon or by overlapping peripheral neuropathies.
Method: We retrospectively compared electrophysiologic data of 35 ALS patients to 50 age-matched healthy control subjects. We further compared electrophysiologic data of the ALS patients with peripheral neuropathies to those who had none, to evaluate the influence of concurrent peripheral neuropathies on the thenar muscular atrophy.
Results: All ALS patients showed prolonged motor latencies and decreased sensory amplitudes in median nerve conduction study, compared to those in ulnar nerve conduction study. Healthy subjects did not show a difference between median and ulnar nerve conduction studies. The patients with ALS showed delayed latencies and amplitudes of median nerve CMAP, regardless of the presence of peripheral neuropathies.
Conclusion: The selective thenar atrophy in ALS is prominently due to the pathophysiological disease progression, regardless of the presence of concomitant peripheral neuropathies.
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등록된 정보가 없습니다.
참고문헌 (14)
참고문헌 신청
Anderew E / 2012 / The split hand syndrome in amyotrophic lateral sclerosis / J Neurol Neurosurg Psychiatry 83 : 399 ~ 403
Daniel D / 2001 / Electrodiagnostic medicine / Hanley & Belfus Inc : 1062 ~
Felsenthal G / 1979 / Carpal tunnel syndrome diagnosis / Arch Phys Med Rehabil 58 : 131 ~ 138
Iglesias C / 2015 / Electrophysiological and spinal imaging evidences for sensory dysfunction in amyotrophic lateral sclerosis / BMJ Open 24 : 1 ~ 10
Kawamura Y / 1981 / Morphometric comparison of the vulnerability of peripheral motor and sensory neurons in amyotrophic lateral sclerosis / J Neuropathol Exp Neurol 40 : 667
Daniel D / 2001 / Electrodiagnostic medicine / Hanley & Belfus Inc : 1062 ~
Felsenthal G / 1979 / Carpal tunnel syndrome diagnosis / Arch Phys Med Rehabil 58 : 131 ~ 138
Iglesias C / 2015 / Electrophysiological and spinal imaging evidences for sensory dysfunction in amyotrophic lateral sclerosis / BMJ Open 24 : 1 ~ 10
Kawamura Y / 1981 / Morphometric comparison of the vulnerability of peripheral motor and sensory neurons in amyotrophic lateral sclerosis / J Neuropathol Exp Neurol 40 : 667
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