지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
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Objectives : By investigating antimicrobial activity of natural extracts, identifying its usefulness as antibiotic material to oral bacteria.
Methods : Antimicrobial activity tests of 25 natural extracts were implemented on 6 type strains alleged to cause dental caries and 10 clinical strains isolated and identified from dental caries.
Results : Among medicinal plants, Coptis japonica, Scutellaria baicalensis, Dictamnus dasycarpus showed antimicrobial activity. Among lichens, 3 methanol extracts and 6 acetone extracts showed antimicrobial activity. Minimum Inhibitory Concentration(MIC) test of Usnea aurantiacoatra KoLRI 004184, an acetone extract of lichen with the highest antimicrobial activity, on 6 type strains involved in dental caries and 10 strains isolated from dental caries resulted as follows; Actinomyces oris 1041 12㎍/ml, for Corynebacterium durum 3151 13㎍/ml, for Rothia dentocariosa KCTC 3204T 14㎍/ml, for R. dentocariosa 911 15㎍/ml, for R. dentocariosa 1822 12㎍/ml, for Lactobacillus casei KACC 12413T12㎍/ml, for L. acidophilus KACC 12419T 16㎍/ml, for L. rhamnosus 2421 15㎍/ml, for Streptococcus mutans KCTC 3065T 15 ㎍/ml, for S. mutans 121 13㎍/ml, for Streptococcus oralis 2221 18㎍/ml, for S. salivarius KCTC 5512 14㎍/ml, for S. salivarius 122 12㎍/ml, for S. sanguinis KCTC 3284T 14㎍/ml, for S. sanguinis 912 14㎍/ml, for Neisseria sp. KEM232 12㎍/ml.
Conclusions : Even a small amount of extract from lichen Usnea aurantiacoatra KoLRI 004184 showed very high level of antimicrobial activation against all 16 bacterial strains involved in dental caries.
목차
등록된 정보가 없습니다.
참고문헌 (30)
참고문헌 신청
Babita Paudel-Bhattarai / 2009 / Isolation and characterization of antibacterial and antioxidant compounds from the antarctic lichen Ramalina terebrata / 박사 / 순천향대학교 대학원
CLSI / 2009 / Performance standards for antimicrobial susceptibility testing / Clinical and Laboratory Standards Institute : M100 ~ S119
Crittenden PD / 1995 / Attempted isolation and success in the culturing of a broad spectrum of lichen-forming and lichenicolous fungi / The New phytologist 130 (2) : 267 ~ 2
Ingolfsdottir K / 2002 / Usnic acid / Phytochemistry 61 (7) : 729 ~ 736
Jarvinen H / 1993 / In vitro susceptibility of Streptococcus mutans to chlorhexidine and six other antimicrobial agents / Antimicrob Agents Chemother 37 (5) : 1158 ~ 1159
CLSI / 2009 / Performance standards for antimicrobial susceptibility testing / Clinical and Laboratory Standards Institute : M100 ~ S119
Crittenden PD / 1995 / Attempted isolation and success in the culturing of a broad spectrum of lichen-forming and lichenicolous fungi / The New phytologist 130 (2) : 267 ~ 2
Ingolfsdottir K / 2002 / Usnic acid / Phytochemistry 61 (7) : 729 ~ 736
Jarvinen H / 1993 / In vitro susceptibility of Streptococcus mutans to chlorhexidine and six other antimicrobial agents / Antimicrob Agents Chemother 37 (5) : 1158 ~ 1159
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