지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
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Objectives: Coriolus versicolor is an edible mushroom with physiological activities that has been used in traditional medicine. The aim of this study was to investigate the antimicrobial activity of extracts obtained from Coriolus versicolor against oral pathogens. Methods: The antimicrobial activities of various extracts of Coriolus versicolor were examined by disc diffusion assay, and minimum inhibitory concentration (MIC) of these extracts were also was determined by broth dilution method. The growth inhibition effect of extracts was measured at 600 nm for 12 hrs against Streptococcus ratti, Streptococcus criceti, Aggregatibacter actinomycetemcomitans, Actinomyces viscosus, and Actinomyces israelii. Results: Coriolus versicolor extracts showed antimicrobial activities against all nine oral pathogens through disc diffusion assay. The ethanol extract and ethyl acetate extract differed significantly compared with acetone extract against Streptococcus ratti, Streptococcus criceti, Actinomyces viscosus, Actinomyces israelii and Aggregatibacter actinomycetemcomitans (p<0.05). These extracts exhibited MIC ranges of 2.63 to >10.50 mg/ml against the tested bacteria. The ethanol extract from Coriolus versicolor showed lower MIC values of 2.63 to 5.25 mg/ml. According to the obtained growth curve, the extracts of Coriolus versicolor were more effective against Actinomyces viscosus. Conclusions: The acetone, ethanol, and ethyl acetate extracts from Coriolus versicolor showed antimicrobial activities against Streptococcus mutans, Staphylococcus aureus, Streptococcus sanguinis, Streptococcus sobrinus, Streptococcus ratti, Streptococcus criceti, Aggregatibacter actinomycetemcomitans, Actinomyces viscosus, and Actinomyces israeli.i Therefore, they could be considered as natural oral antimicrobial agents against oral pathogens.
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참고문헌 (28)
참고문헌 신청
Akio Yanagida / 2000 / Inhibitory Effects of Apple Polyphenols and Related Compounds on Cariogenic Factors of Mutans Streptococci / Journal of Agricultural and Food Chemistr
Anne D. Haffajee / 1994 / Microbial etiological agents of destructive periodontal diseases / Periodontology 2000 5 (1) : 78 ~ 111
Armitage GC / 1999 / Development of a classification system for periodontal diseases and conditions / Ann Periodontol 79 : 31 ~ 35
C.J. Tredwin / 2016 / Drug-induced Disorders of Teeth / Journal of Dental Research 84 (7) : 596 ~ 602
Choi JL / 2006 / Antimicrobial effect of mulberry leaves extracts against oral microorganism / J Dent Hyg Sci 6 : 251 ~ 254
Anne D. Haffajee / 1994 / Microbial etiological agents of destructive periodontal diseases / Periodontology 2000 5 (1) : 78 ~ 111
Armitage GC / 1999 / Development of a classification system for periodontal diseases and conditions / Ann Periodontol 79 : 31 ~ 35
C.J. Tredwin / 2016 / Drug-induced Disorders of Teeth / Journal of Dental Research 84 (7) : 596 ~ 602
Choi JL / 2006 / Antimicrobial effect of mulberry leaves extracts against oral microorganism / J Dent Hyg Sci 6 : 251 ~ 254
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