지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
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Objectives : The aim of the study is to investigate the antimicrobial activity of jaborandi and sorbitol to various oral microbes.
Methods : Jaborandi leaves contain pilocarpine. The conditions for extraction were optimized on the basis of substances, temperatures and pHs. Total pilocarpine content after extraction was analyzed by HPLC. The herbal antimicrobial activity of jaborandi and sorbitol were evaluated for oral microbes containing ATCC 25175 S. mutans, ATCC 13419 S. salivarius, ATCC 6249 S.
mitis, ATCC 33398 S. equi, ATCC 29213 S. aureus, ATCC 14053 C. albicans.
Results : The optimum conditions for highest yielding extraction were pilocarpine content after boiling at 100oC for 1 hour at pH 3. The level of total pilocarpine content was analyzed at 833 mg/kg by HPLC. The most effective antimicrobial activity was obtained by combination of pilocarpine and sorbitol rather than pilocarpine, menthol and sorbitol, respectively.
Conclusions : This results supported the preventive oral health care using safe and convenient jaborandi herb.
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참고문헌 (26)
참고문헌 신청
Abreu IN de / 2005 / Production of pilocarpine in callus of jaborandi (Pilocarpus microphyllus Stapf) / In Vitro Cell Dev Biol Plant 41 (6) : 806 ~ 811
Avancini G / 2003 / Induction of pilocarpine formation in Jaborandi leaves by salicylic acid and methyljasmonate / Phytochemistry 63 : 171 ~ 175
Baik SH / 2004 / The effects of xylitol and sorbitol on oral health and xerostomia in Korean elderly / 박사 / Univ. of Ewha Womans
Berlin J / 1986 / Biotechnology / VCH : 629 ~
Chung HY / 2000 / In vitro studies on the superoxide scavenging activitiesm the cytotoxic and the immunomodulating effects of thirteen kinds of herbal extracts / Korean J Foo
Avancini G / 2003 / Induction of pilocarpine formation in Jaborandi leaves by salicylic acid and methyljasmonate / Phytochemistry 63 : 171 ~ 175
Baik SH / 2004 / The effects of xylitol and sorbitol on oral health and xerostomia in Korean elderly / 박사 / Univ. of Ewha Womans
Berlin J / 1986 / Biotechnology / VCH : 629 ~
Chung HY / 2000 / In vitro studies on the superoxide scavenging activitiesm the cytotoxic and the immunomodulating effects of thirteen kinds of herbal extracts / Korean J Foo
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