지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한치매학회 Dementia and Neurocognitive Disorders(대한치매학회지) Dementia and Neurocognitive Disorders(대한치매학회지) 제15권 제1호
- 발행연도
- 2016.1
- 수록면
- 24 - 27 (4page)
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초록· 키워드
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BackgroundHashimoto’s encephalopathy (HE) and anti N-methyl-D-aspartate receptor (NMDAR) encephalitis have clinical overlaps.
Case ReportA 70-year-old woman presented with acutely developed confusion, disorientations and psychosis. HE was suspected based on goiter, markedly elevated anti-thyroglobulin and anti-thyroid peroxidase antibody. She was placed on high dose steroid and intravenous immunoglobulins administration, which did not ameliorate her symptoms. After the antibodies to the NMDAR were identified, weekly 500 mg of rituximab with 4 cycles were started. The current followed up indicated a complete recovery.
ConclusionsThe possible associations between NMDAR antibody and autoimmune thyroid antibodies in anti-NMDAR encephalitis with positive thyroid autoantibodies remain unclear. However, a trend toward a higher incidence of NMDAR antibody in patients with autoimmune thyroid antibodies than without has been observed. Cases of encephalitis with only NMDAR antibody (pure anti-NMDAR encephalitis) also occur. Therefore, it is important for clinicians to know the clinical and pathogenic differences between anti-NMDAR encephalitis with positive thyroid autoantibody and pure anti-NMDAR encephalitis for relevant treatment, predicting prognosis, and future follow-up.
목차
등록된 정보가 없습니다.
참고문헌 (7)
참고문헌 신청
Titulaer MJ / 2013 / Treatment and prognostic factors for long-term outcome in patients with anti-NMDA receptor encephalitis : an observational cohort study / Lancet Neurol 12:157~165
Tamagno G / 2006 / Clinical and diagnostic aspects of encephalopathy associated with autoimmune thyroid disease(or Hashimoto’s encephalopathy) / Intern Emerg Med 1:15~23
Punzi L / 2004 / Chronic autoimmune thyroiditis and rheumatic manifestations / Joint Bone Spine 71:275~283
Tüzün E / 2011 / Autoantibodies to neuronal surface antigens in thyroid antibodypositive and-negative limbic encephalitis / Neurol India 59:47~50
Prüss H / 2010 / Retrospective analysis of NMDA receptor antibodies in encephalitis of unknown origin / Neurology 75:1735~1739
Tamagno G / 2006 / Clinical and diagnostic aspects of encephalopathy associated with autoimmune thyroid disease(or Hashimoto’s encephalopathy) / Intern Emerg Med 1:15~23
Punzi L / 2004 / Chronic autoimmune thyroiditis and rheumatic manifestations / Joint Bone Spine 71:275~283
Tüzün E / 2011 / Autoantibodies to neuronal surface antigens in thyroid antibodypositive and-negative limbic encephalitis / Neurol India 59:47~50
Prüss H / 2010 / Retrospective analysis of NMDA receptor antibodies in encephalitis of unknown origin / Neurology 75:1735~1739
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