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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 179 - 193 (15page)
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초록· 키워드
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Objectives: Nigella sativa (black seed or black cumin), which belongs to the Ranunculacea family, is an annual herb with many pharmacological properties. Among its many active constituents, thymoquinone (TQ) is the most abundant constituent of the volatile oil of Nigella sativa (N. sativa) seeds, and it is the constituent to which most properties of this herb are attributed.
Methods: PubMed-Medline, Scopus, and Web of Science databases were searched to identify randomized control trials (RCTs) investigating the therapeutic effects of N. sativa and/or TQ. In this review, we investigated the clinical uses of N. sativa and TQ in the prevention and the treatment of different diseases and morbidity conditions in humans.
Results: Black seed and TQ are shown to possess multiple useful effects for the treatment of patients with several diseases, such as inflammatory and auto-immune disorders, as well as metabolic syndrome. Also, other advantages, including antimicrobial, anti-nociceptive and anti-epileptic properties, have been documented. The side effects of this herbal medicine appear not to be serious, so it can be applied in clinical trials because of its many advantages.
Conclusion: Some effects of N. sativa, such as its hypoglycemic, hypolipidemic and bronchodilatory effects, have been sufficiently studied and are sufficiently understood to allow for the next phase of clinical trials or drug developments. However, most of its other effects and applications require further clinical and animal studies.
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등록된 정보가 없습니다.
참고문헌 (24)
참고문헌 신청
Abukhader MM / 2013 / Thymoquinone in the clinical treatment of cancer : fact or fiction? / Pharmacogn Rev 7 (14) : 117 ~ 120
Ahmad A / 2013 / A review on therapeutic potential of Nigella sativa: a miracle herb / Asian Pac J Trop Biomed 3 (5) : 337 ~ 352
Ali BH / 2003 / Pharmacological and toxicological properties of Nigella sativa / Phytother Res 17 (4) : 299 ~ 305
Amin B / 2014 / Effects of intraperitoneal thymoquinone on chronic neuropathic pain in rats / Planta Med 80 (15) : 1269 ~ 1277
Amin B / 2015 / Black Cumin (Nigella sativa)and its active constituent, thymoquinone: an overview on the analgesic and anti-inflammatory effects / Planta Med 82 (1-2) : 8 ~
Ahmad A / 2013 / A review on therapeutic potential of Nigella sativa: a miracle herb / Asian Pac J Trop Biomed 3 (5) : 337 ~ 352
Ali BH / 2003 / Pharmacological and toxicological properties of Nigella sativa / Phytother Res 17 (4) : 299 ~ 305
Amin B / 2014 / Effects of intraperitoneal thymoquinone on chronic neuropathic pain in rats / Planta Med 80 (15) : 1269 ~ 1277
Amin B / 2015 / Black Cumin (Nigella sativa)and its active constituent, thymoquinone: an overview on the analgesic and anti-inflammatory effects / Planta Med 82 (1-2) : 8 ~
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