지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 12 - 20 (9page)
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초록· 키워드
오류제보하기
Objective: Standard cancer therapy prolongs survival,but can be detrimental to the quality of life,compromise the immune system, and leave residual disease that can cause recurrence years or decades in the future. Tumor dormancy therapy is a novel therapeutic approach that may improve these shortcomings, promote quality of life, and prolong survival. The aim of this study was to analyze studies on dormancy therapy, especially studies using traditional Oriental herbal medicine, so as to evaluate the efficacy of dormancy therapy with traditional oriental herbal medicine.
Methods: We conducted a systematic literature review using Scientific and Technical Information Integration Services (NDSL), PubMed, and RISS. We searched for clinical reports, papers, and books related to tumor metastasis, recurrence, immunotherapy, tumor dormancy, and traditional oriental herbal medicine with anticancer effects. Seventy-nine (79) experimental and clinical articles in both Korean and English were reviewed. This study was conducted from March 1,2012 to May 31, 2012.
Results: This approach, Tumor dormancy therapy,rather than seeking to remove the tumor, includes combination of low-dose chemotherapy, immunotherapy,immunosurveillance, and other methods to stabilize tumor growth and to enhance the host is immunity against disseminated tumor cells and thus to manage cancer as a chronic disease while maintaining quality of life. In particular, integrative use of Oriental herbal medicine has been shown to induce or maintain tumor dormancy, increase the effectiveness of conventional chemotherapy, improve quality of life, and prolong survival.
Conclusion: Tumor dormancy therapy is a promising novel therapeutic approach that may be especially effective with Oriental herbal medicine. Further research is needed to determine its potential mechanisms and therapeutic applications.
목차
등록된 정보가 없습니다.
참고문헌 (26)
참고문헌 신청
Aguirre-Ghiso JA / 2007 / Models, mechanisms and clinical evidence for cancer dormancy / Nat Rev Cancer 7 (11) : 834 ~ 846
Barkan D / 2008 / Inhibition of metastatic outgrowth from single dormant tumor cells by targeting the cytoskeleton / Cancer Res 68 (15) : 6241 ~ 6250
Becker S / 2007 / Primary systemic therapy does not eradicate disseminated tumor cells in breast cancer patients / Breast Cancer Res Treat 106 (2) : 239 ~ 243
Black WC / 1993 / Advances in diagnostic imaging and overestimations of disease prevalence and the benefits of therapy / N Engl J Med 328 (17) : 1237 ~ 1243
Brackstone M / 2007 / Tumour dormancy in breast cancer: an update / Breast Cancer Res 9 (3) : 208 ~
Barkan D / 2008 / Inhibition of metastatic outgrowth from single dormant tumor cells by targeting the cytoskeleton / Cancer Res 68 (15) : 6241 ~ 6250
Becker S / 2007 / Primary systemic therapy does not eradicate disseminated tumor cells in breast cancer patients / Breast Cancer Res Treat 106 (2) : 239 ~ 243
Black WC / 1993 / Advances in diagnostic imaging and overestimations of disease prevalence and the benefits of therapy / N Engl J Med 328 (17) : 1237 ~ 1243
Brackstone M / 2007 / Tumour dormancy in breast cancer: an update / Breast Cancer Res 9 (3) : 208 ~
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